49ers vs Cardinals Prediction Betting Tips & Picks 12/17/2023

by | Dec 14, 2023

SITPicks.com 9 Picks 9 NFL 9 49ers vs Cardinals Prediction Betting Tips & Picks 12/17/2023


The 49ers (9-3) and the Cardinals (3-10) play at State Farm Stadium on December 17, 2023. Find more below on the 49ers vs. Cardinals betting line, injury report, head-to-head stats, best bets and more.
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The Cardinals are ready to soar with a 13.5 point lead against the 49ers – can they reach the total of 48?

49ers vs Cardinals Spread and Betting Line

49ers vs Cardinals Betting Information
Favorite Spread Favorite spread odds Underdog spread odds Total Over total odds Under total odds
Cardinals +13.5 -110 -110 48 -110 -110

49ers vs. Cardinals Game Info

  • Game Day: Sunday, December 17, 2023
  • Game Time: 04:05 PM ET
  • TV Channel:
  • Stadium: State Farm Stadium

49ers vs Cardinals Prediction and Computer Picks

Prediction for 49ers vs Cardinals
Spread Pick Total Pick Predicted Score
49ers (-13.5) Under (49) 49ers 10, Cardinals 37

49ers Leaders

  • This season, Brock Purdy has thrown like a champion – 3553 yards, 25 TDs, and only 7 interceptions on 359 attempts!

  • Christian McCaffrey is tearing up the turf this season, leading the team in rushing with 1177 yards, a whopping 72-yard long, and 12 touchdowns!

  • Brandon Aiyuk is making waves this season, leading the team with 1053 yards on 56 receptions and 24 touchdowns!

  • Nick Bosa is dominating the field with an impressive 9.5 sacks and 28 total tackles this year!

  • Fred Warner has been a defensive powerhouse this season, dominating the field with 67 solo tackles, 2 sacks, and 67 interceptions!

49ers Season Stats

Stat Average (Total)
Pass yards 297(3560)
Rush yards 151(1815)
Points scored 29(380)
Turnovers 1(10)
Points allowed 16(205)

49ers Leaders

  • Kyler Murray is making his mark this season with 864 yards, 130 attempts, 3 touchdowns and only 2 interceptions!

  • James Conner is tearing up the field this season! He’s currently leading the team in rushing with 631 yards, a long of 35 and 4 touchdowns!

  • Trey McBride is soaring to the top with 610 yards on 56 receptions and 4 touchdowns – setting the team standard!

  • Dennis Gardeck is dominating the field with 5 sacks and 30 total tackles – leading the team in both categories this year!

  • Kyzir White has been an unstoppable force on defence this season, racking up 53 solo tackles, 2 sacks, and 1 interception – leading the team all the way!

Cardinals Season Stats

Stat Average (Total)
Pass yards 71.2(926)
Rush yards 95.1(1236)
Points scored 18(230)
Turnovers 0(4)
Points allowed 25(331)

49ers and Cardinals Injury Report

Injury Report for 49ers and Cardinals
Player Pos. Injury Status
Elijah Mitchell RB knee Out
Ross Dwelley TE Out
Javon Hargrave DT hamstring Questionable
Dre Greenlaw LB hip Questionable
Arik Armstead DE foot/knee Out
Charvarius Ward CB groin Questionable
Oren Burks LB Out
Spencer Burford OT knee Out
Darrell Luter Jr. CB hamstring Out
Ray-Ray McCloud III WR ribs Injured Reserve
George Odum S biceps Injured Reserve
Talanoa Hufanga S knee Injured Reserve
Nick Zakelj OT Injured Reserve
Drake Jackson DE knee Injured Reserve
Danny Gray WR shoulder Injured Reserve
Cameron Latu TE knee Injured Reserve

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