White Sox vs. Cubs Prediction, Betting Tips & Picks 5/28/2022

The Chicago Cubs (18-26) enter Saturday’s matchup with the Chicago White Sox (22-22) following their 2-2 series tie with the Reds. The White Sox, coming off of a series loss against the Red Sox, are listed as -145 favorites for Game 1. The series begins at Guaranteed Rate Field, starting at 7:15 PM ET. The White Sox’s Johnny Cueto and the Cubs’ Keegan Thompson have been named the starters for this contest.

White Sox vs. Cubs Spread and Betting Line

Computer Predictions for White Sox vs. Cubs

Our computer pick: Chicago Cubs (+125) and Over (8.5)

White Sox vs. Cubs Game Info

• Chicago White Sox probable starting pitcher: Johnny Cueto
• Chicago Cubs probable starting pitcher: Keegan Thompson
• Game Day: Saturday, May 28, 2022
• Game Time: 7:15 PM ET
• Location: Chicago, Illinois
• Stadium: Guaranteed Rate Field

Chicago White Sox vs Chicago Cubs Pitching Matchup

White Sox Starter Johnny Cueto

• Cueto (0-0) starts for the White Sox, his third this season.
• His last appearance was on Sunday against the New York Yankees, when the righty went six scoreless innings while allowing six hits.
• In two games this season, he has put up a .00 ERA and averages 9.0 strikeouts per nine innings while opposing batters are hitting .190 against him.
• Cueto is seeking his third quality start in a row.
• Cueto will look to continue a three-game streak of lasting five or more innings (he’s averaging 6.0 innings per appearance).
• The opposing Cubs offense has the 16th-ranked slugging percentage (.385) and ranks 14th in MLB play with 44 home runs. It has a collective .234 batting average, and is 18th in MLB with 341 total hits and 11th in MLB play scoring 192 runs.

Cubs Starter Keegan Thompson

• Thompson will take to the mound for the Cubs, his third start of the season.
• The right-hander last pitched out of the bullpen on Sunday, when he threw three innings, giving up one earned run while allowing two hits to the Arizona Diamondbacks.
• He has pitched to a 1.54 ERA this season with 8.0 strikeouts per nine innings compared to 2.6 walks per nine across 10 games.
• In two starts this season, Thompson has lasted five or more innings one time, with an average of 3.2 innings per appearance.
• The White Sox have scored 161 runs this season, which ranks 25th in MLB. They are batting .234 for the campaign with 39 home runs, 20th in the league.
• This season, the right-hander has pitched against the White Sox in one game, and they have gone 4-for-12 with a home run and an RBI over 3 2/3 innings.

White Sox Betting Picks & Insights

• The White Sox have entered the game as favorites 33 times this season and won 18, or 54.5%, of those games.
• The White Sox have a record of 5-10, a 33.3% win rate, when they’re favored by -145 or more by sportsbooks this season.
• The White Sox have a 59.2% chance to win this game based on the implied probability of the moneyline.
• Games involving the White Sox have gone over the total set by sportsbooks in 18 of 48 chances this season.
• The White Sox are 22-26-0 against the spread this season.

Cubs Betting Picks & Insights

• The Cubs have been chosen as underdogs in 29 games this year and have walked away with the win 12 times (41.4%) in those games.
• This year, the Cubs have won eight of 16 games when listed as at least +125 or better on the moneyline.
• The Cubs have an implied victory probability of 44.4% according to the moneyline set by oddsmakers for this matchup.
• The Cubs and their opponents have hit the over in 22 of their 44 games with a total this season.
• In 44 games with a line this season, the Cubs have a mark of 23-21-0 against the spread.

White Sox Leaders & Batting Stats

• Tim Anderson is the White Sox best hitter, putting together an average of .363 while also being the team’s top run producer, delivering 19 RBI and crushing five home runs.
• Anderson is 70th in home runs and 94th in RBI among all hitters in MLB.
• Jose Abreu has been productive as he paces his team with 19 runs batted in.
• Abreu is 70th in home runs in the majors, and 94th in RBI.
• Abreu heads into this game looking for his seventh game in a row with a hit. During his last 10 games he is batting .371 with six doubles, two home runs, eight walks and seven RBI.
• Andrew Vaughn has driven in a team-high 19 runs batted in.
• Vaughn is on a four-game hitting streak entering this contest. In his last five games he is batting .438 with two doubles, a home run, a walk and six RBI.
• Gavin Sheets is hitting .207 with three doubles, four home runs and 10 walks.

Cubs Leaders & Batting Stats

• Ian Happ paces the Cubs with 25 runs batted in while putting up a team-best batting average of .275.
• In all of the majors, Happ ranks 70th in homers and 27th in RBI.
• Happ carries a two-game hitting streak into this matchup. In his last five games he is batting .316 with three doubles, two home runs, two walks and seven RBI.
• Willson Contreras is hitting .260 with seven doubles, a triple, six home runs and 17 walks.
• Contreras is currently 48th in home runs and 141st in RBI in the major leagues.
• Seiya Suzuki is batting .245 with 12 doubles, a triple, four home runs and 21 walks.
• Patrick Wisdom has put up a team-high 10 home runs.

Betting Tips for White Sox vs. Cubs

We have the Cubs on the moneyline at +125 on the moneyline as our best bet in this contest after looking at all of the key trends and stats for this matchup. Our computer prediction sees the scoring going over the total of 8.5 runs.