Cleveland Guardians vs. Kansas City Royals MLB Betting Tips and Best Bets

The Cleveland Guardians are moneyline favorites (-125) to begin their season with a road win over the Kansas City Royals on Thursday at 4:10 PM ET. Cleveland’s Shane Bieber and Kansas City’s Zack Greinke have been named the starters for this contest.

Cleveland Guardians vs. Kansas City Royals: Predictions, Betting Odds, Spread, Line

Computer Predictions for Guardians vs. Royals

Our computer pick: Kansas City Royals (+106) and Over (8)

Guardians vs. Royals Game Info

• Cleveland Guardians probable starting pitcher: Shane Bieber
• Kansas City Royals probable starting pitcher: Zack Greinke
• Game Day: Thursday, April 7, 2022
• Game Time: 4:10 PM ET
• Location: Kansas City, Missouri
• Stadium: Kauffman Stadium

Cleveland Guardians vs Kansas City Royals Pitching Matchup

Guardians Starter Shane Bieber

• Bieber starts for the first time this season for the Guardians.
• When he last appeared on Friday, Oct. 1, the 26-year-old right-hander started the game and went 3 2/3 innings against the Kansas City Royals.
• Last season he finished with a 3.17 ERA and a 1.21 WHIP over his 16 games, putting together a 7-4 record.

Royals Starter Zack Greinke

• Greinke will make his first start of the season for the Royals.
• The 38-year-old right-hander hasn’t pitched since last season. He last appeared on Sunday, Oct. 31 against the Atlanta Braves, when he pitched 4 2/3 scoreless innings as the starter.
• He finished last season with a 4.16 ERA and a 1.17 WHIP while earning an 11-6 record.
• Among qualified pitchers in the majors last year, he ranked 29th in ERA (4.16), 21st in WHIP (1.170), and 36th in K/9 (6.3).

Guardians Betting Picks & Insights

• Last season, the Guardians were favored 65 times and won 39, or 60%, of those games.
• Cleveland was 31-19 last season when entering a game favored by -125 or more on the moneyline.
• The moneyline for this contest implies a 55.6% chance of a victory for the Guardians.
• Last season, Cleveland and its opponents hit the over in 82 of their 157 games with a total.
• The Guardians were 58-53-0 against the spread last season.

Royals Betting Picks & Insights

• The Royals won in 46, or 41.8%, of the 110 contests they were named as odds-on underdogs in last year.
• Last year, Kansas City won 37 of 86 games when listed as at least +106 on the moneyline.
• The Royals have an implied victory probability of 48.5% according to the moneyline set for this matchup.
• Kansas City and its opponents went over in 68 of their 159 games with a total set by sportsbooks last season.
• The Royals had an against the spread mark of 54-59-0 in 113 games with a line last season.

Guardians Leaders & Batting Stats

• Jose Ramirez had 36 home runs and 103 runs batted in last season.
• Myles Straw hit .271 with 29 doubles, a triple, four home runs and 67 walks.
• Amed Rosario had a batting average of .282 with 155 total hits last season.
• Franmil Reyes had 18 doubles, two triples, 30 home runs and 43 walks while hitting .254.

Royals Leaders & Batting Stats

• Whit Merrifield hit .277 a season ago with 42 doubles, three triples, 10 home runs and 40 walks.
• Salvador Perez had 48 home runs and 121 RBI a season ago.
• Carlos Santana hit .214 last season with 15 doubles, 19 home runs and 86 walks.
• Nicky Lopez hit .300 a season ago with 149 hits.

Betting Tips for Guardians vs. Royals

We have the Royals on the moneyline at +106 on the moneyline as our best bet in this game after digging through all of the key statistics and trends for this matchup. Our computer prediction sees the scoring going over the total of 8 runs.