Giants vs. Athletics Prediction, Betting Tips & Picks 4/27/2022

The San Francisco Giants (13-5) roll into Wednesday’s matchup with the Oakland Athletics (9-9) looking to extend a five-game winning streak. The contest starts at 9:45 PM ET with the Giants listed as -145 favorites on the moneyline. Oakland is expected to give the ball to Paul Blackburn, while San Francisco has yet to name a starting pitcher.

Giants vs. Athletics Spread and Betting Line

Computer Predictions for Giants vs. Athletics

Our computer pick: Oakland Athletics (+125) and Over (7.5)

Giants vs. Athletics Game Info

• Oakland Athletics probable starting pitcher: Paul Blackburn
• Game Day: Wednesday, April 27, 2022
• Game Time: 9:45 PM ET
• Location: San Francisco, California
• Stadium: Oracle Park

Athletics Starter Paul Blackburn

• Blackburn has been named the starter for the Athletics and will make his first start this season.
• The right-hander is making his first start of the year. The 28-year-old did not make an appearance on the mound last season.
• The Giants are batting .238 this season, 13th in MLB. They have a team slugging percentage of .392 (11th in the league) with 21 home runs.

Giants Betting Picks & Insights

• The Giants have been favorites in 13 games this season and won 11 (84.6%) of those contests.
• San Francisco has entered seven games this season favored by -145 or more and is 5-2 in those contests.
• The Giants have a 59.2% chance to win this game based on the implied probability of the moneyline.
• San Francisco and its opponents have gone over the total this season in seven of their 19 opportunities.
• In 18 games with a spread this season, the Giants are 11-7-0 ATS.

Athletics Betting Picks & Insights

• The Athletics have been chosen as underdogs in 13 games this year and have walked away with the win six times (46.2%) in those games.
• Oakland has a mark of 5-6 in contests where sportsbooks favor them by +125 or worse on the moneyline.
• The moneyline set for this matchup implies the Athletics have a 44.4% chance of coming away with a victory in the contest.
• Contests with Oakland have gone over the total set by sportsbooks in eight of 18 chances this season.
• In 18 games with a line this season, the Athletics have a mark of 10-8-0 against the spread.

Giants Leaders & Batting Stats

• Joc Pederson leads the Giants with six home runs.
• Thairo Estrada is batting .258 with three doubles, two home runs and four walks.
• Estrada ranks 60th in homers and 23rd in RBI in the majors.
• Wilmer Flores has racked up a team-best batting average of .283 while leading the Giants in runs batted in (12).
• Brandon Belt is hitting .258 with a double, a triple, four home runs and 11 walks.

Athletics Leaders & Batting Stats

• Sean Murphy has racked up a team-best three home runs.
• Among all hitters in the big leagues, Murphy is 29th in homers and 23rd in RBI.
• Sheldon Neuse is batting .327 to lead the lineup.
• Neuse is 121st in home runs and 49th in RBI among all MLB batters this year.
• Seth Brown paces the Athletics with 13 runs batted in.
• Tony Kemp is batting .250 with a double and nine walks.

Betting Tips for Giants vs. Athletics

We have the Athletics on the moneyline at +125 on the moneyline as our best bet in this game after looking at all of the key stats and trends for this matchup. Our computer picks see the scoring going over the total of 7.5 runs.