White Sox vs. Royals Prediction, Betting Tips & Picks 4/27/2022

The Chicago White Sox (6-10) hope to avoid their ninth straight defeat when they host the Kansas City Royals (6-9) Wednesday at 2:10 PM ET on NBCS-CHI. The White Sox are listed as -179 favorites to snap their losing skid, while the Royals are +155 underdogs. Dylan Cease starts for Chicago while Zack Greinke is Kansas City’s starter for the contest.

White Sox vs. Royals Spread and Betting Line

Computer Predictions for White Sox vs. Royals

Our computer pick: Kansas City Royals (+155) and Over (7.5)

White Sox vs. Royals Game Info

• Chicago White Sox probable starting pitcher: Dylan Cease
• Kansas City Royals probable starting pitcher: Zack Greinke
• Game Day: Wednesday, April 27, 2022
• Game Time: 2:10 PM ET
• TV Channel: NBCS-CHI
• Location: Chicago, Illinois
• Stadium: Guaranteed Rate Field

Chicago White Sox vs Kansas City Royals Pitching Matchup

White Sox Starter Dylan Cease

• Cease makes the start for the White Sox, his fourth of the season. He is 2-1 with a 3.38 ERA and 19 strikeouts in 16 innings pitched.
• The righty last pitched on Thursday against the Cleveland Guardians, when he went 5 1/3 innings, allowing four earned runs while giving up eight hits.
• The 26-year-old has amassed an ERA of 3.38, with 10.7 strikeouts per nine innings, in three games this season. Opponents are batting .217 against him.
• Cease is seeking his third straight outing lasting five or more innings. He averages 5.1 innings per appearance on the hill.
• He will match up with a Royals offense that ranks 28th in MLB with 106 total hits (on a .215 batting average). The team also slugs a collective .333 (25th in MLB) with 11 total home runs (24th in MLB).
• Among qualifying pitchers in MLB play this season, the 26-year-old’s 3.38 ERA ranks 31st, 1.250 WHIP ranks 39th, and 10.7 K/9 ranks eighth.

Royals Starter Zack Greinke

• Greinke (0-1) will take to the mound for the Royals and make his fourth start of the season.
• The right-hander gave up one earned run in five innings pitched on Thursday in his last outing, a matchup with the Minnesota Twins.
• The 38-year-old has an ERA of 2.25, a 0.667 strikeout to walk ratio and a WHIP of 1.188 in three games this season.
• Greinke will look to pitch five or more innings for the third start in a row.
• The White Sox rank 24th in MLB with a .211 batting average this season. They have a team slugging percentage that ranks 23rd in the league (.339) and 14 home runs.
• The 38-year-old ranks 16th in ERA (2.25), 36th in WHIP (1.188), and 55th in K/9 (1.1) among qualified pitchers in the majors this season.

White Sox Betting Picks & Insights

• The White Sox have won six, or 50%, of the 12 games they’ve played as favorites this season.
• Chicago has not entered a game this season as a bigger favorite on the moneyline than the -179 odds on them winning this game.
• The sportsbooks’ moneyline implies a 64.2% chance of a victory for the White Sox.
• So far this season, Chicago and its opponents have hit the over in eight of their 17 games with a total.
• The White Sox are 5-12-0 ATS in their 17 games with a spread this season.

Royals Betting Picks & Insights

• The Royals have been chosen as underdogs in 10 games this year and have walked away with the win four times (40%) in those games.
• Kansas City has played as an underdog of +155 or more just one time this year and came away with a loss in that game.
• The Royals have an implied victory probability of 39.2% according to the moneyline set by sportsbooks for this matchup.
• Kansas City and their opponents have hit the over in five of their 15 games with a total set by oddsmakers this season.
• The Royals have posted a record of 8-7-0 against the spread this season.

White Sox Leaders & Batting Stats

• Tim Anderson paces the White Sox with a .288 batting average.
• Anderson’s home runs place him 60th in MLB, and he is 125th in RBI.
• Andrew Vaughn’s three home runs and eight runs batted in both pace his team.
• Jose Abreu is batting .218 with three doubles, two home runs and seven walks.
• Abreu is on a three-game hitting streak entering this contest. In his last five games he is batting .222 with a double, a home run, three walks and two RBI.
• Luis Robert is batting .205 with two doubles, two home runs and a walk.

Royals Leaders & Batting Stats

• Salvador Perez paces the Royals in home runs (five) and runs batted in (eight).
• Among all hitters in the majors, Perez’s home run total is fifth and his RBI tally is 67th.
• Perez carries a two-game hitting streak into this matchup. During his last five outings he is hitting .222 with two doubles, a home run, two walks and two RBI.
• Andrew Benintendi is hitting .389 to lead the lineup.
• Benintendi is 121st in homers and 101st in RBI among all MLB hitters this season.
• Hunter Dozier is hitting .278 with three doubles, a triple, three home runs and two walks.
• Michael A. Taylor has a home run and eight walks while hitting .205.

Betting Tips for White Sox vs. Royals

We have the Royals on the moneyline at +155 on the moneyline as our best bet in this game after taking a look at all of the key stats and trends for this matchup. Our computer picks see the scoring going over the total of 7.5 runs.