Astros vs. Mariners Prediction, Betting Tips & Picks 5/4/2022

The Houston Astros (13-11) hope to complete a three-game sweep of the Seattle Mariners (12-12) when the teams meet at 2:10 PM ET Wednesday. The Astros are -194 favorites to keep the Mariners out of the win column in the series. Justin Verlander starts for Houston while Matt Brash is Seattle’s starter for the contest.

Astros vs. Mariners Spread and Betting Line

Computer Predictions for Astros vs. Mariners

Our computer pick: Seattle Mariners (+165) and Over (7.5)

Astros vs. Mariners Game Info

• Houston Astros probable starting pitcher: Justin Verlander
• Seattle Mariners probable starting pitcher: Matt Brash
• Game Day: Wednesday, May 4, 2022
• Game Time: 2:10 PM ET
• Location: Houston, Texas
• Stadium: Minute Maid Park

Houston Astros vs Seattle Mariners Pitching Matchup

Astros Starter Justin Verlander

• Verlander (2-1 with a 1.73 ERA and 28 strikeouts in 26 innings pitched) gets the start for the Astros, his fifth of the season.
• The right-hander’s most recent time out was on Thursday against the Texas Rangers, when he went seven innings, surrendering one earned run while giving up four hits.
• In four games this season, the 39-year-old has a 1.73 ERA and 9.7 strikeouts per nine innings, while allowing a batting average of .161 to his opponents.
• Verlander is looking for his fourth quality start in a row.
• Verlander will aim to pitch five or more innings for his fifth straight appearance. He’s averaging 6.2 frames per outing.
• The opposing Mariners offense has the 13th-ranked slugging percentage (.378) and is 12th in MLB play with 23 home runs. It has a collective .232 batting average, and is 11th in MLB with 185 total hits and 12th in MLB play scoring 102 runs.
• Verlander has thrown eight innings without giving up an earned run on three hits, while striking out eight against the Mariners this season.
• This season, the 39-year-old ranks 11th in ERA (1.73), first in WHIP (.692), and 16th in K/9 (9.7) among pitchers who qualify.

Mariners Starter Matt Brash

• Brash (1-2) will take to the mound for the Mariners and make his fifth start of the season.
• The right-hander gave up six earned runs in two innings pitched on Friday in his last outing, a matchup with the Miami Marlins.
• The 23-year-old has pitched in four games this season with an ERA of 6.88 and 8.5 strikeouts per nine innings, with an opponent batting average of .286.
• In four starts this season, Brash has lasted five or more innings two times, with an average of 4.1 innings per appearance.
• The Astros rank 27th in MLB with a .215 batting average this season. They have a team slugging percentage that ranks 16th in the league (.375) and 29 home runs.
• The Astros have gone 2-for-14 with a home run and two RBI in one game against the right-hander this season.

Astros Betting Picks & Insights

• This season, the Astros have won 10 out of the 16 games, or 62.5%, in which they’ve been favored.
• Houston has not entered a game this season as a bigger favorite on the moneyline than the -194 odds on them winning this game.
• The moneyline for this contest implies a 66% chance of a victory for the Astros.
• Houston and its opponents have hit the over in seven of their 24 games with a total this season.
• The Astros are 12-12-0 against the spread in their 24 chances this season.

Mariners Betting Picks & Insights

• The Mariners have been chosen as underdogs in 16 games this year and have walked away with the win six times (37.5%) in those games.
• Seattle has yet to play a game this season with longer moneyline odds than +165.
• The Mariners have an implied victory probability of 37.7% according to the moneyline set for this matchup.
• Seattle and their opponents have hit the over in 11 of their 24 games with a total set by oddsmakers this season.
• In 24 games with a line this season, the Mariners have a mark of 14-10-0 against the spread.

Astros Leaders & Batting Stats

• Yordan Alvarez has homered eight times this season, the highest mark on the Astros, while hitting .265 with 14 RBI.
• Of all hitters in baseball, Alvarez’s home run total places him second, and his RBI tally puts him 25th.
• Alvarez has collected a hit in two straight games. During his last five outings he is batting .353 with four home runs, four walks and six RBI.
• Alex Bregman has four doubles, four home runs and 14 walks while batting .220.
• Bregman is 28th in home runs in MLB, and 38th in RBI.
• Kyle Tucker has a team-best 15 runs batted in.
• Jeremy Pena is hitting .229 with three doubles, a triple, five home runs and seven walks.
• Pena is riding a two-game hitting streak into this one. In his last five games he is hitting .200 with two home runs, a walk and seven RBI.

Mariners Leaders & Batting Stats

• Ty France leads the Mariners in home runs (five) and runs batted in (21).
• Among all hitters in the big leagues, France’s home run total is 17th and his RBI tally ranks third.
• France has collected a hit in three games in a row. In his last five games he is batting .286 with .
• J.P. Crawford has a club-high .357 batting average.
• Among all MLB hitters, Crawford is 28th in homers and 79th in RBI.
• Adam Frazier is batting .240 with five doubles, a triple and eight walks.
• Eugenio Suarez is hitting .198 with six doubles, a triple, three home runs and 12 walks.

Betting Tips for Astros vs. Mariners

After taking a look at all of the key statistics and trends for this matchup, our best bet is the Mariners on the moneyline at +165. Our computer picks see the scoring going over the total of 7.5 runs.