Athletics vs. Orioles Prediction, Betting Tips & Picks 4/21/2022

Seeking their seventh win of the year, the Oakland Athletics (6-6) are favorites (-128) on the moneyline when they take on the Baltimore Orioles (4-8) Thursday at 3:37 PM ET. Oakland’s Paul Blackburn gets the start, and he’ll go against Baltimore’s Tyler Wells.

Athletics vs. Orioles Spread and Betting Line

Computer Predictions for Athletics vs. Orioles

Our computer pick: Baltimore Orioles (+108) and Over (7.5)

Athletics vs. Orioles Game Info

• Oakland Athletics probable starting pitcher: Paul Blackburn
• Baltimore Orioles probable starting pitcher: Tyler Wells
• Game Day: Thursday, April 21, 2022
• Game Time: 3:37 PM ET
• Location: Oakland, California
• Stadium: Oakland Coliseum

Oakland Athletics vs Baltimore Orioles Pitching Matchup

Athletics Starter Paul Blackburn

• Blackburn (0-0) takes the mound for the Athletics to make his second start of the season.
• In his last appearance on Saturday, the right-hander tossed five innings against the Toronto Blue Jays, giving up two earned runs while surrendering five hits.
• In one games this season, he has a 3.60 ERA and 5.4 strikeouts per nine innings, while opponents are batting .263 against him.
• He meets an Orioles offense that ranks last in the league with 24 runs while batting .206 as a squad. It has a collective .284 slugging percentage (28th in MLB play) and has hit a total of four home runs (30th in MLB).

Orioles Starter Tyler Wells

• Wells will get the start for the Orioles, his third of the season.
• The right-hander last pitched on Saturday, when he threw four innings against the New York Yankees without allowing a run.
• He has pitched in two games this season with an ERA of 6.35, a 1.25 strikeout to walk ratio and a WHIP of 1.765.
• The Athletics rank 13th in MLB with 47 runs scored this season. They have a .209 batting average this campaign with eight home runs (23rd in the league).

Athletics Betting Picks & Insights

• The Athletics have entered the game as favorites three times this season and won twice.
• Oakland has played as a favorite of -128 or more twice this season and split those games.
• Oddsmakers have implied with the moneyline set for this matchup that the Athletics have a 56.1% chance to win.
• Games involving Oakland have gone over the total set by oddsmakers in four of 12 chances this season.
• The Athletics are 7-5-0 ATS in their 12 games with a spread this season.

Orioles Betting Picks & Insights

• The Orioles have won in four, or 33.3%, of the 12 contests they have been named as odds-on underdogs in this year.
• Baltimore has a win-loss record of 3-7 when favored by +108 or worse by oddsmakers this year.
• The Orioles have an implied victory probability of 48.1% according to the moneyline set by oddsmakers for this matchup.
• In 12 contests with a total set by bookmakers, Baltimore and its opponents have failed to hit the over in every one of them.
• The Orioles are 7-5-0 against the spread in their 12 games with a line set by sportsbooks this season.

Athletics Leaders & Batting Stats

• Tony Kemp’s .278 average leads the Athletics this year. His resume also includes zero homers and driven in two RBI.
• Among all batters in MLB, Kemp ranks 190th in homers and 206th in RBI.
• Kemp carries a two-game hitting streak into this matchup. During his last five outings he is batting .333 with five walks.
• Sean Murphy’s two home runs pace his team.
• Among all MLB hitters, Murphy ranks 29th in home runs and 36th in RBI.
• Elvis Andrus is batting .184 with three doubles and seven walks.
• Seth Brown’s eight runs batted in are a team-high mark.

Orioles Leaders & Batting Stats

• Anthony Santander leads the team in batting average with a mark of .297.
• Among all hitters in the big leagues, Santander is 78th in homers and 275th in RBI.
• Cedric Mullins has hit two home runs with eight runs batted in, leading the team in both categories.
• Mullins is 29th among all hitters in the majors in homers, and 24th in RBI.
• Austin Hays has three doubles and six walks while hitting .220.
• Jorge Mateo is batting .270 with two doubles and four walks.

Betting Tips for Athletics vs. Orioles

Our best bet is the Orioles on the moneyline at +108 after looking at all of the key trends and stats for this matchup. Our computer predicts the total score will over the total of 7.5 runs.