Blue Jays vs. Reds Prediction, Betting Tips & Picks 5/21/2022

The Toronto Blue Jays (21-18), led by Santiago Espinal on a 13-game hitting streak, will meet the Cincinnati Reds (11-27) Saturday at Rogers Centre. The Blue Jays are -260 favorites for the matchup, which starts at 3:07 PM ET. Alek Manoah will get the ball for Toronto while Cincinnati counter with Hunter Greene.

Blue Jays vs. Reds Spread and Betting Line

Computer Predictions for Blue Jays vs. Reds

Our computer pick: Cincinnati Reds (+214) and Over (8)

Blue Jays vs. Reds Game Info

• Toronto Blue Jays probable starting pitcher: Alek Manoah
• Cincinnati Reds probable starting pitcher: Hunter Greene
• Game Day: Saturday, May 21, 2022
• Game Time: 3:07 PM ET
• Location: Toronto, Ontario
• Stadium: Rogers Centre

Toronto Blue Jays vs Cincinnati Reds Pitching Matchup

Blue Jays Starter Alek Manoah

• Manoah (4-1) gets the starting nod for the Blue Jays in his eighth start of the season. He has a 1.71 ERA in 42 innings pitched, with 39 strikeouts.
• The righty last appeared on Sunday against the Tampa Bay Rays, when he went six innings, allowing one earned run while giving up five hits.
• The 24-year-old has put up an ERA of 1.71, with 8.4 strikeouts per nine innings, in seven games this season. Opponents are hitting .188 against him.
• Manoah heads into the game with six quality starts under his belt this year.
• Manoah will look to last five or more innings for his eighth straight appearance. He’s averaging 6.0 frames per outing.
• He will face a Reds offense that ranks 23rd in the league with 151 runs while batting .219 as a unit. It has a collective .352 slugging percentage (26th in MLB play) and has hit a total of 31 home runs (22nd in MLB).
• The 24-year-old ranks fifth in ERA (1.71), fifth in WHIP (.881), and 25th in K/9 (8.4) among qualifying pitchers in MLB play this season.

Reds Starter Hunter Greene

• Greene (1-6) will take the mound for the Reds, his eighth start of the season.
• The right-hander’s last start was on Sunday, when he tossed 7 1/3 innings while giving up one earned run on zero hits in a matchup with the Pittsburgh Pirates.
• The 22-year-old has pitched to a 6.21 ERA this season with 11.9 strikeouts per nine innings compared to 5.4 walks per nine across seven games.
• In seven starts this season, he’s earned one quality start.
• Greene has pitched five or more innings in two straight games and will look to extend that streak.
• The Blue Jays rank 24th in MLB with 142 runs scored this season. They have a .235 batting average this campaign with 39 home runs (13th in the league).

Blue Jays Betting Picks & Insights

• This season, the Blue Jays have won 17 out of the 29 games, or 58.6%, in which they’ve been favored.
• Toronto has played as a favorite of -260 or more once this season and won that game.
• Oddsmakers have implied with the moneyline set for this matchup that the Blue Jays have a 72.2% chance to win.
• Toronto and its opponents have gone over the total this season in 15 of their 39 opportunities.
• The Blue Jays have an ATS record of 16-23-0 in 39 games with a spread this season.

Reds Betting Picks & Insights

• The Reds have been chosen as underdogs in 33 games this year and have walked away with the win 10 times (30.3%) in those games.
• This season, Cincinnati has been a moneyline underdog of -260 or better three times, losing every contest.
• Bookmakers have implied with the moneyline set for this matchup that the Reds have a 31.8% chance of pulling out a win.
• Cincinnati and their opponents have gone over in 23 of their 39 games with a total set by sportsbooks this season.
• The Reds have an against the spread mark of 18-21-0 in 39 games with a line this season.

Blue Jays Leaders & Batting Stats

• Vladimir Guerrero Jr. has collected a team-high seven home runs.
• In all of the majors, Guerrero ranks 27th in homers and 35th in RBI.
• George Springer has shown his power as he leads his team with seven home runs and 22 RBI.
• Among all MLB hitters, Springer ranks 27th in homers and 25th in RBI.
• Springer heads into this game looking for his fifth game in a row with a hit. During his last five outings he is batting .222 with a triple, two walks and four RBI.
• Espinal leads the Blue Jays with a team-best batting average of .296.
• Espinal will look to build on his 13-game hitting in this matchup. During his last 10 outings he is batting .371 with three doubles, a walk and three RBI.
• Bo Bichette is hitting .242 with eight doubles, four home runs and nine walks.

Reds Leaders & Batting Stats

• Tommy Pham has collected a team-high four home runs.
• Among all hitters in MLB, Pham’s home run total ranks 75th and his RBI tally is 155th.
• Tyler Naquin’s four home runs, 21 RBI and .257 batting average are all tops in the lineup.
• Naquin is 75th in home runs and 35th in RBI among all hitters in the majors.
• Kyle Farmer has 11 doubles, a home run and seven walks while hitting .226.
• Tyler Stephenson has hit a team-best four home runs.

Betting Tips for Blue Jays vs. Reds

After analyzing all of the key statistics and trends for this matchup, our best bet is the Reds on the moneyline at +214. Our computer prediction sees the scoring going over the total of 8 runs.