Cardinals vs. Cubs Prediction, Computer Picks, Odds & Pitching Matchup 8/23/2022

The St. Louis Cardinals (70-52) are set to take on the Chicago Cubs (53-69) Tuesday at 8:05 PM ET. The Cardinals are listed as -134 favorites by oddsmakers, while the underdog Cubs have +114 odds for the contest. Jake Woodford will get the ball for St. Louis while Chicago counter with Adrian Sampson.

Cardinals vs. Cubs Spread and Betting Line

Computer Predictions for Cardinals vs. Cubs

After digging through all of the key trends and statistics for this matchup, our best bet is the Cubs on the moneyline at +114. Our computer picks see the scoring going over the total of 9 runs.

Our computer pick: Chicago Cubs (+114) and Over (9)

Cardinals vs. Cubs Game Info

• St. Louis Cardinals probable starting pitcher: Jake Woodford
• Chicago Cubs probable starting pitcher: Adrian Sampson
• Game Day: Tuesday, August 23, 2022
• Game Time: 8:05 PM ET
• Location: Chicago, Illinois
• Stadium: Wrigley Field

St. Louis Cardinals vs Chicago Cubs Pitching Matchup

Cardinals Starter Jake Woodford

• Woodford will start for the Cardinals, his first this season.
• The 25-year-old right-hander has 13 appearances in relief this season.
• In 13 appearances this season, he has a 2.66 ERA and 4.9 strikeouts per nine innings, while opponents are hitting .241 against him.
• The Cubs are 22nd in MLB action with 505 runs scored this season, and are batting .241 with 126 home runs (15th in baseball).

Cubs Starter Adrian Sampson

• The Cubs’ Sampson (1-3) will make his 11th start of the season.
• The right-hander last pitched on Thursday, when he allowed four hits in 5 2/3 scoreless innings against the Baltimore Orioles.
• The 30-year-old has an ERA of 3.51 and 7.3 strikeouts per nine innings with an opponent batting average of .251 in 12 games this season.
• He has two quality starts in 10 chances this season.
• Sampson has made eight starts of five or more innings in 10 chances this season, and averages 4.3 frames when he pitches.
• The Cardinals are batting .256 this season, sixth in MLB. They have a team slugging percentage of .422 (sixth in the league) with 145 home runs.
• The Cardinals have gone 4-for-19 with a double and two RBI in five innings this season against the right-hander.

Cardinals Betting Picks & Insights

• The Cardinals have been favorites in 72 games this season and won 49 (68.1%) of those contests.
• This season, St. Louis has won 37 of its 53 games, or 69.8%, when favored by at least -134 on the moneyline.
• The implied probability of a win from the Cardinals, based on the moneyline, is 57.3%.
• Games involving St. Louis have gone over the total set by bookmakers in 58 of 125 chances this season.
• The Cardinals have an ATS record of 69-55-0 in 124 games with a spread this season.

Cubs Betting Picks & Insights

• The Cubs have been underdogs in 86 games this season and have come away with the win 36 times (41.9%) in those contests.
• This season, Chicago has come away with a win 23 times in 61 chances when named as an underdog of at least +114 or worse on the moneyline.
• The Cubs have an implied victory probability of 46.7% according to the moneyline set by sportsbooks for this matchup.
• Chicago and its opponents have gone over the total this season in 55 of their 124 opportunities.
• The Cubs are 65-59-0 against the spread in their 124 games that had a posted line this season.

Cardinals Leaders & Batting Stats

• Paul Goldschmidt’s 31 home runs and 100 RBI both lead the Cardinals, on top of his team-high .337 average.
• Of all hitters in the majors, Goldschmidt’s home run total places him third, and his RBI tally puts him third.
• Nolan Arenado has 33 doubles, a triple, 25 home runs and 42 walks while hitting .297.
• Arenado ranks 17th in homers and ninth in RBI in the major leagues.
• Tommy Edman has 20 doubles, three triples, eight home runs and 39 walks while hitting .251.
• Dylan Carlson has 24 doubles, three triples, eight home runs and 35 walks while batting .242.

Cubs Leaders & Batting Stats

• Willson Contreras is batting .248 with 21 doubles, two triples, 20 home runs and 42 walks.
• Among all hitters in the majors, Contreras’ home run total is 34th and his RBI tally ranks 74th.
• Ian Happ has 31 doubles, two triples, 13 home runs and 47 walks while hitting .275.
• Happ is 92nd in homers and 60th in RBI among all hitters in the big leagues.
• Nico Hoerner paces the Cubs’ lineup with a .288 batting average.
• Patrick Wisdom has posted a team-leading 22 home runs and has driven in 58 runs.