Cardinals vs. Cubs Prediction, Computer Picks, Odds & Pitching Matchup 8/24/2022

The St. Louis Cardinals (71-52) will look to Corey Dickerson, red hot after a four-hit game, to lead them in a matchup with the Chicago Cubs (53-70) on Wednesday at 8:05 PM ET. The Cardinals are -224 favorites for the contest, according to sportsbooks. Miles Mikolas will get the ball for St. Louis while Chicago counter with Luke Farrell.

Cardinals vs. Cubs Spread and Betting Line

Computer Predictions for Cardinals vs. Cubs

After taking a look at all of the key stats and trends for this matchup, our best bet is the Cubs on the moneyline at +183. Our computer prediction sees the scoring going over the total of 8.5 runs.

Our computer pick: Chicago Cubs (+183) and Over (8.5)

Cardinals vs. Cubs Game Info

• St. Louis Cardinals probable starting pitcher: Miles Mikolas
• Chicago Cubs probable starting pitcher: Luke Farrell
• Game Day: Wednesday, August 24, 2022
• Game Time: 8:05 PM ET
• Location: Chicago, Illinois
• Stadium: Wrigley Field

St. Louis Cardinals vs Chicago Cubs Pitching Matchup

Cardinals Starter Miles Mikolas

• Mikolas makes the start for the Cardinals, his 26th of the season. He is 10-9 with a 3.32 ERA and 118 strikeouts through 157 1/3 innings pitched.
• In his most recent time out on Saturday against the Arizona Diamondbacks, the right-hander threw 8 2/3 innings, allowing one earned run while surrendering two hits.
• The 34-year-old has put up an ERA of 3.32, with 6.8 strikeouts per nine innings, in 25 games this season. Opponents have a .227 batting average against him.
• Mikolas is trying to build on a second-game quality start streak in this matchup.
• Mikolas will try to extend a three-game streak of going five or more innings (he’s averaging 6.1 innings per outing).
• He will match up with a Cubs offense that is batting .241 as a unit (15th in MLB). It is also slugging a collective .392 (16th in MLB) with 126 total home runs (15th in MLB).
• Mikolas has thrown 17 1/3 innings, giving up eight earned runs on 20 hits while striking out 19 against the Cubs this season.
• The 34-year-old’s 3.32 ERA ranks 28th, 1.023 WHIP ranks 15th, and 6.8 K/9 ranks 49th among qualifying pitchers this season.

Cubs Starter Luke Farrell

• Farrell will make his first start of the season for the Cubs.
• This will be the first start of the season for the 31-year-old right-hander, who has not made an appearance on the mound in over a season.
• The Cardinals rank fifth in MLB with a .258 batting average this season. They have a team slugging percentage that ranks fifth in the league (.425) and 148 home runs.

Cardinals Betting Picks & Insights

• The Cardinals have won 50, or 68.5%, of the 73 games they’ve played as favorites this season.
• St. Louis has been at least a -224 moneyline favorite three times this season and won each of those games.
• Oddsmakers have implied with the moneyline set for this matchup that the Cardinals have a 69.1% chance to win.
• St. Louis and its opponents have gone over the total this season in 59 of their 126 opportunities.
• The Cardinals are 70-55-0 ATS in their 125 games with a spread this season.

Cubs Betting Picks & Insights

• The Cubs have been chosen as underdogs in 87 games this year and have walked away with the win 36 times (41.4%) in those games.
• Chicago has a mark of 2-10 in contests where bookmakers favor them by +183 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Cubs have a 35.3% chance of pulling out a win.
• Contests with Chicago have gone over the total set by oddsmakers in 56 of 125 chances this season.
• The Cubs have posted a record of 65-60-0 against the spread this season.

Cardinals Leaders & Batting Stats

• Paul Goldschmidt is the bat to watch in the Cardinals lineup, leading the team in batting average (.335), home runs (31), and RBI (100).
• In all of Major League Baseball, Goldschmidt ranks third in home runs and third in RBI.
• Goldschmidt carries a two-game hitting streak into this matchup. During his last five outings he is batting .261 with a home run, a walk and four RBI.
• Nolan Arenado is hitting .301 with 33 doubles, a triple, 26 home runs and 42 walks.
• Arenado is 12th in home runs and ninth in RBI among all MLB hitters this season.
• Tommy Edman is hitting .252 with 21 doubles, three triples, nine home runs and 39 walks.
• Dylan Carlson is batting .243 with 24 doubles, four triples, eight home runs and 35 walks.

Cubs Leaders & Batting Stats

• Willson Contreras is batting .248 with 21 doubles, two triples, 20 home runs and 42 walks.
• Among all hitters in the big leagues, Contreras is 34th in home runs and 76th in RBI.
• Ian Happ is hitting .274 with 31 doubles, two triples, 13 home runs and 47 walks.
• Among all MLB hitters, Happ is 92nd in homers and 62nd in RBI.
• Nico Hoerner paces the Cubs with a team-best batting average of .286.
• Patrick Wisdom has posted a team-high 22 home runs and has driven in 58 runs.