Cardinals vs. Cubs Prediction, Computer Picks, Odds & Pitching Matchup 9/4/2022

The St. Louis Cardinals (78-55) will play the Chicago Cubs (56-77) on Sunday at 2:15 PM ET. Willson Contreras will be looking for his 98th hit of the season for the underdog Cubs (+159) when the game gets underway at Busch Stadium. Miles Mikolas will get the ball for St. Louis while Chicago counter with Marcus Stroman.

Cardinals vs. Cubs Spread and Betting Line

Computer Predictions for Cardinals vs. Cubs

Our best bet is the Cubs on the moneyline at +159 after looking at all of the key statistics and trends for this matchup. Our computer projects the scoring will over the total of 7.5 runs.

Our computer pick: Chicago Cubs (+159) and Over (7.5)

Cardinals vs. Cubs Game Info

• St. Louis Cardinals probable starting pitcher: Miles Mikolas
• Chicago Cubs probable starting pitcher: Marcus Stroman
• Game Day: Sunday, September 4, 2022
• Game Time: 2:15 PM ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium

St. Louis Cardinals vs Chicago Cubs Pitching Matchup

Cardinals Starter Miles Mikolas

• Mikolas makes the start for the Cardinals, his 28th of the season. He is 10-10 with a 3.48 ERA and 124 strikeouts through 168 1/3 innings pitched.
• His most recent appearance was on Monday against the Cincinnati Reds, when the righty went 4 1/3 innings, surrendering four earned runs while giving up six hits.
• The 34-year-old has an ERA of 3.48, with 6.6 strikeouts per nine innings, in 27 games this season. Opponents have a .231 batting average against him.
• Mikolas enters this matchup with 18 quality starts under his belt this season.
• Mikolas has pitched five or more innings in a game 24 times this year entering this outing.
• The opposing Cubs offense has a collective .241 batting average, and is 16th in the league with 1085 total hits and 22nd in MLB action with 547 runs scored. It has the 15th-ranked slugging percentage (.390) and ranks 17th in home runs (134) in all of MLB.
• Mikolas has thrown 24 innings, giving up 11 earned runs on 26 hits while striking out 22 against the Cubs this season.
• Among qualifying pitchers in MLB play this season, the 34-year-old’s 3.48 ERA ranks 32nd, 1.040 WHIP ranks 14th, and 6.6 K/9 ranks 46th.

Cubs Starter Marcus Stroman

• Stroman (3-6) will take to the mound for the Cubs and make his 20th start of the season.
• The right-hander’s last start was on Tuesday, when he tossed five innings while giving up one earned run on three hits in a matchup with the Toronto Blue Jays.
• The 31-year-old has an ERA of 3.98, a 2.931 strikeout to walk ratio and a WHIP of 1.210 in 19 games this season.
• In 19 starts this season, he’s earned a quality start in seven of them.
• Stroman has three starts in a row of five innings or more.
• The Cardinals rank sixth in MLB with a .258 batting average this season. They have a team slugging percentage that ranks third in the league (.431) and 169 home runs.
• The Cardinals have gone 26-for-68 with three doubles, five home runs and 17 RBI in 15 2/3 innings this season against the right-hander.

Cardinals Betting Picks & Insights

• The Cardinals have been favorites in 80 games this season and won 55 (68.8%) of those contests.
• This season, St. Louis has won 12 of its 19 games, or 63.2%, when favored by at least -189 on the moneyline.
• The Cardinals have a 65.4% chance to win this game based on the implied probability of the moneyline.
• St. Louis’ games have gone over the total in 65 of their 136 chances.
• The Cardinals are 77-58-0 against the spread this season.

Cubs Betting Picks & Insights

• The Cubs have been underdogs in 96 games this season and have come away with the win 39 times (40.6%) in those contests.
• This year, Chicago has won seven of 26 games when listed as at least +159 or worse on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Cubs have a 38.6% chance of pulling out a win.
• Chicago and their opponents have hit the over in 60 of their 135 games with a total set by oddsmakers this season.
• The Cubs have an against the spread mark of 69-66-0 in 135 games with a line this season.

Cardinals Leaders & Batting Stats

• Paul Goldschmidt leads the Cardinals in home runs (34), runs batted in (107) and has accumulated a team-best batting average of .331.
• Among all batters in the majors, Goldschmidt is fourth in homers and second in RBI.
• Nolan Arenado is batting .305 with 36 doubles, a triple, 28 home runs and 43 walks.
• Among all major league hitters, Arenado is 12th in homers and fifth in RBI.
• Tommy Edman has 25 doubles, four triples, 13 home runs and 39 walks while hitting .260.
• Edman will look to build on his six-game hitting in this game. During his last 10 outings he is hitting .341 with four doubles, a triple, four home runs and eight RBI.
• Dylan Carlson has 24 doubles, four triples, eight home runs and 38 walks while batting .241.

Cubs Leaders & Batting Stats

• Ian Happ has plated a team-leading 63 runs batted in.
• Happ is 78th in home runs and 49th in RBI among all hitters in the majors.
• Contreras has 22 doubles, two triples, 21 home runs and 42 walks while hitting .246.
• Contreras is 37th overall in homers and 81st in RBI this season.
• Nico Hoerner has accumulated a team-best batting average of .283.
• Seiya Suzuki is batting .263 with 21 doubles, a triple, 10 home runs and 35 walks.