The Cincinnati Reds (2-11) will try to end their nine-game losing streak when they host the St. Louis Cardinals (7-4) on Friday at 6:40 PM ET. Sportsbooks consider the Cardinals to be -125 favorites for the contest, while the Reds are +106 underdogs looking for the upset. St. Louis’ Steven Matz gets the start, and he’ll go against Cincinnati’s Hunter Greene.
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Cardinals vs. Reds Spread and Betting Line
| Favorite | Favorite Moneyline | Underdog Moneyline | Total | Over Total Odds | Under Total Odds | Spread | Favorite Spread Odds | Underdog Spread Odds |
|---|---|---|---|---|---|---|---|---|
| Cardinals | -125 | +106 | 8.5 | -116 | -104 | -1.5 | +128 | -151 |
Computer Predictions for Cardinals vs. Reds
Our computer pick: Cincinnati Reds (+106) and Over (8.5)
Cardinals vs. Reds Game Info
- St. Louis Cardinals probable starting pitcher: Steven Matz
- Cincinnati Reds probable starting pitcher: Hunter Greene
- Game Day: Friday, April 22, 2022
- Game Time: 6:40 PM ET
- Location: Cincinnati, Ohio
- Stadium: Great American Ball Park
St. Louis Cardinals vs Cincinnati Reds Pitching Matchup
| Matz | Greene | |
|---|---|---|
| 2 | GS | 2 |
| 1-1 | W-L | 1-1 |
| 7.27 | ERA | 4.35 |
| 8.2 | IP | 10.1 |
| 1 | BB | 2 |
| 11 | SO | 13 |
Cardinals Starter Steven Matz
- Matz (1-1) takes the mound for the Cardinals to make his third start of the season.
- His last time out was on Saturday against the Milwaukee Brewers, when the lefty threw 5 2/3 scoreless innings while giving up three hits.
- In two appearances this season, he has compiled a 7.27 ERA and averages 11.4 strikeouts per nine innings while opposing batters are hitting .316 against him.
- The opposing Reds offense has the worst slugging percentage (.277) and is 21st in MLB play with nine home runs. It has a collective .177 batting average, and is 27th in MLB with 73 total hits and 25th in MLB play scoring 37 runs.
Reds Starter Hunter Greene
- Greene will take to the mound for the Reds, his third start of the season.
- The right-hander’s last appearance was on Sunday, when he threw 5 1/3 innings, giving up two earned runs while allowing five hits against the Los Angeles Dodgers.
- He has pitched in two games this season with an ERA of 4.35, a batting average against of .231 and 11.3 strikeouts per nine innings.
- Greene has pitched five or more innings in two straight games and will look to extend that streak.
- The Cardinals rank 13th in MLB with 50 runs scored this season. They have a .235 batting average this campaign with 13 home runs (sixth in the league).
Cardinals Betting Picks & Insights
- This season, the Cardinals have won four out of the five games in which they’ve been favored.
- This season, St. Louis has won three of its four games when favored by at least -125 on the moneyline.
- Sportsbooks have implied with the moneyline set for this matchup that the Cardinals have a 55.6% chance to win.
- St. Louis’ games have gone over the total in five of their 11 chances.
- The Cardinals have an ATS record of 7-4-0 in 11 games with a spread this season.
Reds Betting Picks & Insights
- The Reds have been underdogs in 11 games this season and have come away with the win two times (18.2%) in those contests.
- This season, Cincinnati has been victorious two times in 11 chances when named as an underdog of at least +106 or longer on the moneyline.
- The moneyline set for this matchup implies the Reds have a 48.5% chance of walking away with the win.
- Contests with Cincinnati have gone over the total set by sportsbooks in seven of 13 chances this season.
- The Reds have an against the spread record of 4-9-0 in 13 games with a line this season.
Cardinals Leaders & Batting Stats
- Not only does Nolan Arenado lead the Cardinals in hitting with his .405 average, he also is their premier power option with five home runs and 14 RBI.
- Of all batters in the majors, Arenado is second in home runs and third in RBI.
- Tommy Edman has a double, a triple, three home runs and three walks while batting .342.
- Edman is 13th in homers in baseball, and 40th in RBI.
- Edman has 10 straight games with at least one hit. In his last 10 outings he is batting .353 with a double, a triple, two home runs, three walks and six RBI.
- Tyler O’Neill is hitting .231 with a double, a home run and six walks.
- Albert Pujols is batting .333 with a double, two home runs and two walks.
- Pujols brings a four-game streak with at least one hit into this one. In his last five games he is batting .438 with a double, two home runs, two walks and four RBI.
| Name | GP | BA | OBP | SLG | HR | RBI | H |
|---|---|---|---|---|---|---|---|
| Nolan Arenado | 11 | .405 | .468 | .881 | 5 | 14 | 17 |
| Tommy Edman | 11 | .342 | .390 | .658 | 3 | 7 | 13 |
| Tyler O’Neill | 11 | .231 | .319 | .333 | 1 | 7 | 9 |
| Albert Pujols | 6 | .333 | .417 | .667 | 2 | 4 | 7 |
| Paul Goldschmidt | 11 | .146 | .271 | .195 | 0 | 1 | 6 |
Reds Leaders & Batting Stats
- The Reds are lead in runs batted in by Kyle Farmer with a mark of six, he also leads the team in hitting, posting an average of .289.
- Among all hitters in MLB, Farmer ranks 195th in homers and 57th in RBI.
- Tommy Pham has shown his power as he paces his team with two home runs.
- Among all MLB hitters, Pham ranks 33rd in homers and 164th in RBI.
- Jake Fraley is batting .129 with a double, a home run and four walks.
- Brandon Drury has swatted a team-high two long balls.
| Name | GP | BA | OBP | SLG | HR | RBI | H |
|---|---|---|---|---|---|---|---|
| Kyle Farmer | 13 | .289 | .347 | .356 | 0 | 6 | 13 |
| Tommy Pham | 11 | .158 | .256 | .342 | 2 | 3 | 6 |
| Jake Fraley | 11 | .129 | .229 | .258 | 1 | 3 | 4 |
| Brandon Drury | 10 | .192 | .250 | .500 | 2 | 4 | 5 |
| Colin Moran | 7 | .176 | .300 | .176 | 0 | 1 | 3 |
Betting Tips for Cardinals vs. Reds
After digging through all of the key statistics and trends for this matchup, our best bet is the Reds on the moneyline at +106. Our computer picks see the scoring going over the total of 8.5 runs.

