Cleveland Guardians vs. Cincinnati Reds MLB Betting Tips and Best Bets

Coming off of a 2-2 series split with the Royals, the Cleveland Guardians (2-2) are -120 favorites to pick up the win in Game 1 of a two-game series against the Cincinnati Reds (2-2). The series begins at Great American Ball Park, starting on Tuesday at 4:10 PM ET. Cleveland’s Shane Bieber gets the start, and he’ll go against Cincinnati’s Tyler Mahle.

Cleveland Guardians vs. Cincinnati Reds: Predictions, Betting Odds, Spread, Line

Computer Predictions for Guardians vs. Reds

Our computer pick: Cincinnati Reds (+100) and Over (8.5)

Guardians vs. Reds Game Info

• Cleveland Guardians probable starting pitcher: Shane Bieber
• Cincinnati Reds probable starting pitcher: Tyler Mahle
• Game Day: Tuesday, April 12, 2022
• Game Time: 4:10 PM ET
• Location: Cincinnati, Ohio
• Stadium: Great American Ball Park

Cleveland Guardians vs Cincinnati Reds Pitching Matchup

Guardians Starter Shane Bieber

• Bieber (0-0) makes the start for the Guardians, his second of the season.
• The righty last appeared on Thursday against the Kansas City Royals, when he tossed 4 2/3 innings, allowing one earned run while giving up three hits.
• Over his one games this season, opposing hitters have compiled a batting average of only .167 against him. He has a 1.93 ERA and averages 7.7 strikeouts per nine innings.
• Among qualifying pitchers in MLB action this season, the 26-year-old ranks 38th in ERA (1.93), 16th in WHIP (.643), and 55th in K/9 (7.7).

Reds Starter Tyler Mahle

• The Reds’ Mahle will make his second start of the season.
• The right-hander’s last appearance was on Friday, when he threw five innings, giving up no earned runs while allowing three hits against the Atlanta Braves.
• He has pitched to a .00 ERA this season with 12.6 strikeouts per nine innings compared to 3.6 walks per nine across one games.
• Among qualified pitchers this season, the 27-year-old’s .00 ERA ranks first, 1.000 WHIP ranks 29th, and 12.6 K/9 ranks 14th.

Guardians Betting Picks & Insights

• Last season, the Guardians won 39 out of the 65 games, or 60%, in which they were favored.
• Last season, Cleveland won 37 of its 58 games, or 63.8%, when favored by at least -120 on the moneyline.
• The implied probability of a win by the Guardians, based on the moneyline, is 54.5%.
• Games involving Cleveland went over the total set by oddsmakers in 82 of 157 chances last season.
• In 111 games with a spread last season, the Guardians were 58-53-0 ATS.

Reds Betting Picks & Insights

• The Reds were underdogs in 60 games last season and came away with the win 25 times (41.7%) in those contests.
• Cincinnati had a mark of 23-29 in contests where sportsbooks set them as +100 or longer on the moneyline.
• The Reds have an implied victory probability of 50% according to the moneyline set for this matchup.
• Cincinnati and its opponents hit the over in 81 of their 160 games with a total set by oddsmakers last season.
• In 117 games with a line last season, the Reds had a mark of 54-63-0 against the spread.

Guardians Leaders & Batting Stats

• Jose Ramirez had 36 home runs and 103 runs batted in last season.
• Myles Straw hit .271 with 29 doubles, a triple, four home runs and 67 walks.
• Amed Rosario racked up 155 hits with a batting average of .282 last season.
• Franmil Reyes hit .254 with 18 doubles, two triples, 30 home runs and 43 walks.

Reds Leaders & Batting Stats

• Joey Votto had 36 home runs and 99 runs batted in last season.
• Jonathan India had a .269 batting average with 143 hits.
• Tommy Pham hit .229 last season with 24 doubles, two triples, 15 home runs and 78 walks.
• Tyler Naquin had 24 doubles, two triples, 19 home runs and 35 walks while hitting .270.

Betting Tips for Guardians vs. Reds

We have the Reds on the moneyline at +100 on the moneyline as our best bet in this game after analyzing all of the key trends and stats for this matchup. Our computer prediction sees the scoring going over the total of 8.5 runs.