Cubs vs. Diamondbacks Prediction, Betting Tips & Picks 5/22/2022

Led by Patrick Wisdom (two-game homer streak), the Chicago Cubs (15-24) are favorites versus the Arizona Diamondbacks (21-21) Sunday at 2:20 PM ET. Oddsmakers have named the Cubs as -123 favorites for the game. Wade Miley will get the ball for Chicago while Arizona counter with Merrill Kelly.

Cubs vs. Diamondbacks Spread and Betting Line

Computer Predictions for Cubs vs. Diamondbacks

Our computer pick: Arizona Diamondbacks (+104)

Cubs vs. Diamondbacks Game Info

• Chicago Cubs probable starting pitcher: Wade Miley
• Arizona Diamondbacks probable starting pitcher: Merrill Kelly
• Game Day: Sunday, May 22, 2022
• Game Time: 2:20 PM ET
• Location: Chicago, Illinois
• Stadium: Wrigley Field

Chicago Cubs vs Arizona Diamondbacks Pitching Matchup

Cubs Starter Wade Miley

• Miley (1-0) pitches for the Cubs to make his third start of the season.
• In his most recent time out on Monday, the lefty threw seven scoreless innings against the Pittsburgh Pirates while surrendering one hit.
• In two appearances this season, he has compiled a 2.70 ERA and averages 6.3 strikeouts per nine innings while opposing batters are hitting .171 against him.
• He will take the hill against a Diamondbacks offense that is batting .210 as a unit (29th in MLB). It is also slugging a collective .371 (20th in MLB) with 50 total home runs (sixth in MLB).

Diamondbacks Starter Merrill Kelly

• The Diamondbacks will hand the ball to Kelly (3-2) for his ninth start of the season.
• The right-hander’s last appearance was on Wednesday, when he threw two innings against the Los Angeles Dodgers, giving up eight earned runs while allowing five hits.
• The 33-year-old has an ERA of 3.27, a 2.667 strikeout to walk ratio and a WHIP of 1.273 in eight games this season.
• He has started eight games this season, earning a quality start (6 or more IP, 3 or fewer ER) in four of them.
• In eight starts this season, Kelly has lasted five or more innings six times, with an average of 5.2 innings per appearance.
• The Cubs have scored 161 runs this season, which ranks 18th in MLB. They are batting .231 for the campaign with 35 home runs, 18th in the league.
• Among qualified pitchers in the majors this year, the 33-year-old ranks 31st in ERA (3.27), 49th in WHIP (1.273), and 31st in K/9 (8.2).

Cubs Betting Picks & Insights

• The Cubs have won four, or 33.3%, of the 12 games they’ve played as favorites this season.
• Chicago has a record of 3-8, a 27.3% win rate, when favored by -123 or more by sportsbooks this season.
• The Cubs have a 55.2% chance to win this game based on the implied probability of the moneyline.
• So far this season, Chicago and its opponents have hit the over in 18 of their 39 games with a total.
• The Cubs are 20-19-0 ATS in their 39 games with a spread this season.

Diamondbacks Betting Picks & Insights

• The Diamondbacks have been underdogs in 41 games this season and have come away with the win 20 times (48.8%) in those contests.
• This season, Arizona has been victorious 18 times in 38 chances when named as an underdog of at least +104 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Diamondbacks have a 49% chance of pulling out a win.
• Arizona’s games have gone over the total in 20 of their 47 opportunities.
• The Diamondbacks have an against the spread record of 28-19-0 in 47 games with a line this season.

Cubs Leaders & Batting Stats

• Willson Contreras is hitting .258 with seven doubles, a triple, five home runs and 16 walks.
• In all of Major League Baseball, Contreras ranks 58th in homers and 131st in RBI.
• Ian Happ is batting .269 to pace his team.
• Happ ranks 128th in home runs and 76th in RBI in the bigs.
• Seiya Suzuki has a team-high 19 runs batted in.
• Wisdom’s eight home runs and 19 RBI are both team-highs.
• Wisdom has recorded at least one hit in two straight games. During his last five outings he is hitting .111 with two home runs, a walk and two RBI.

Diamondbacks Leaders & Batting Stats

• Christian Walker has swatted a team- leading 10 home runs.
• Walker ranks sixth in homers and 68th in RBI among all hitters in MLB.
• Daulton Varsho’s 20 RBI and .262 batting average both pace his team.
• Among all MLB hitters, Varsho ranks 30th in home runs and 53rd in RBI.
• David Peralta is hitting .225 with six doubles, seven home runs and 18 walks.
• Ketel Marte has 13 doubles, a triple, two home runs and 13 walks while hitting .230.

Betting Tips for Cubs vs. Diamondbacks

We have the Diamondbacks on the moneyline at +104 on the moneyline as our best bet in this contest after looking at all of the key trends and statistics for this matchup.