Houston Astros vs. Arizona Diamondbacks MLB Betting Tips and Best Bets

The Arizona Diamondbacks (1-3) will try to end their three-game losing streak when they host the Houston Astros (3-1) on Tuesday at 9:40 PM ET. Sportsbooks consider the Astros to be -120 favorites for the contest, while the Diamondbacks are +100 underdogs looking for the upset. Luis Garcia starts for Houston while Zac Gallen is Arizona’s starter for the contest.

Houston Astros vs. Arizona Diamondbacks: Predictions, Betting Odds, Spread, Line

Computer Predictions for Astros vs. Diamondbacks

Our computer pick: Arizona Diamondbacks (+100) and Over (9.5)

Astros vs. Diamondbacks Game Info

• Houston Astros probable starting pitcher: Luis Garcia
• Arizona Diamondbacks probable starting pitcher: Zac Gallen
• Game Day: Tuesday, April 12, 2022
• Game Time: 9:40 PM ET
• Location: Phoenix, Arizona
• Stadium: Chase Field

Houston Astros vs Arizona Diamondbacks Pitching Matchup

Astros Starter Luis Garcia

• Garcia will start for the Astros, his first of the season.
• The 25-year-old righty started and threw 2 2/3 innings when he last appeared Wednesday, Nov. 3 against the Atlanta Braves.
• Last season he finished with an 11-8 record, a 3.48 ERA and a 1.178 WHIP over his 30 games.

Diamondbacks Starter Zac Gallen

• Gallen will make his first start of the season for the Diamondbacks.
• The last time the 26-year-old righty pitched was on Sunday, Oct. 3, throwing six innings as the starter against the Colorado Rockies.
• He finished last season with a 4.30 ERA and a 1.294 WHIP while earning a 4-10 record.

Astros Betting Picks & Insights

• Last season, the Astros won 87 out of the 143 games, or 60.8%, in which they were favored.
• Last season, Houston won 80 of its 128 games, or 62.5%, when favored by at least -120 on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Astros have a 54.5% chance to win.
• Last season, Houston and its opponents hit the over in 93 of their 175 games with a total.
• In 130 games with a spread last season, the Astros were 67-63-0 ATS.

Diamondbacks Betting Picks & Insights

• The Diamondbacks were victorious in 39, or 28.5%, of the 137 contests they were chosen as underdogs in last season.
• Last year, Arizona won 33 of 124 games when listed as at least +100 on the moneyline.
• The moneyline set for this matchup implies the Diamondbacks have a 50% chance of walking away with the win.
• Arizona and its opponents went over the total last season in 88 of their 159 opportunities.
• The Diamondbacks went 56-60-0 against the spread in their 116 games that had a posted line last season.

Astros Leaders & Batting Stats

• Jose Altuve hit .278 a season ago with 32 doubles, a triple, 31 home runs and 66 walks.
• Kyle Tucker had 37 doubles, three triples, 30 home runs and 53 walks while hitting .294.
• Yordan Alvarez had 33 home runs and 104 runs batted in last season.
• Michael Brantley hit .311 with 29 doubles, three triples, eight home runs and 33 walks.

Diamondbacks Leaders & Batting Stats

• David Peralta drove in 63 runs last season, while batting .259.
• Ketel Marte hit 14 home runs on the season while slugging .532.
• Pavin Smith had 133 hits with a batting average of .267 last season.
• Christian Walker hit .244 with 23 doubles, a triple, 10 home runs and 38 walks.

Betting Tips for Astros vs. Diamondbacks

After looking at all of the key stats and trends for this matchup, our best bet is the Diamondbacks on the moneyline at +100. Our computer prediction sees the scoring going over the total of 9.5 runs.