The Los Angeles Angels (7-4) and the Houston Astros (6-5) meet in the rubber match of a three-game series on Wednesday at 6:40 PM ET. The Angels are -135 favorites on the moneyline to win the series over the Astros (+115). Los Angeles’ Shohei Ohtani and Houston’s Jake Odorizzi have been named the starters for this contest.
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Los Angeles Angels vs. Houston Astros: Predictions, Betting Odds, Spread, Line
| Favorite | Favorite Moneyline | Underdog Moneyline | Total | Over Total Odds | Under Total Odds | Spread | Favorite Spread Odds | Underdog Spread Odds |
|---|---|---|---|---|---|---|---|---|
| Angels | -135 | +115 | 8.5 | -113 | -106 | -1.5 | +128 | -152 |
Computer Predictions for Angels vs. Astros
Our computer pick: Houston Astros (+115) and Over (8.5)
Angels vs. Astros Game Info
- Los Angeles Angels probable starting pitcher: Shohei Ohtani
- Houston Astros probable starting pitcher: Jake Odorizzi
- Game Day: Wednesday, April 20, 2022
- Game Time: 6:40 PM ET
- Location: Houston, Texas
- Stadium: Minute Maid Park
Los Angeles Angels vs Houston Astros Pitching Matchup
| Ohtani | Odorizzi | |
|---|---|---|
| 0 | GS | 2 |
| 0-1 | W-L | 0-1 |
| 1.93 | ERA | 6.48 |
| 4.2 | IP | 8.1 |
| 1 | BB | 3 |
| 9 | SO | 3 |
Angels Starter Shohei Ohtani
- Ohtani makes his first start of the season for the Angels.
- The 27-year-old right-hander came out of the bullpen in his last outing this season, his only action so far.
- Opposing hitters have compiled a batting average of just .222 against him this season. He has a 1.93 ERA and 17.4 strikeouts per nine innings over his one games.
- The Astros have MLB’s 18th-ranked scoring offense (41 total runs) and have put up a .213 batting average as a team while hitting 14 home runs (third in the league) this season.
Astros Starter Jake Odorizzi
- Odorizzi will take to the mound for the Astros, his third start of the season.
- The right-hander last pitched on Saturday against the Seattle Mariners, throwing 4 1/3 innings and giving up four earned runs.
- He has an ERA of 6.48, a batting average against of .378 and 3.2 strikeouts per nine innings in two games this season.
- The Angels rank fourth in MLB with 54 runs scored this season. They have a .253 batting average this campaign with 14 home runs (third in the league).
- The right-hander has allowed the Angels to go 6-for-18 with a double and two RBI in four innings this season.
Angels Betting Picks & Insights
- The Angels have won six of the eight games they’ve played as favorites this season.
- Los Angeles has played as a favorite of -135 or more once this season and won that game.
- The bookmakers’ moneyline implies a 57.4% chance of a victory for the Angels.
- Los Angeles and its opponents have gone over the total this season in five of their 11 opportunities.
- The Angels have an ATS record of 6-5-0 in 11 games with a spread this season.
Astros Betting Picks & Insights
- The Astros have been victorious in two of the three contests they have been chosen as underdogs in this season.
- This is the worst odds of a win that sportsbooks have given Houston this season with a +115 moneyline set for this game.
- The moneyline set for this matchup implies the Astros have a 46.5% chance of walking away with the win.
- Houston and their opponents have hit the over in five of their 11 games with a total set by oddsmakers this season.
- The Astros are 5-6-0 against the spread in their 11 games with a line set by sportsbooks this season.
Angels Leaders & Batting Stats
- Ohtani has homered three times this season, the highest mark on the Angels, while hitting .213 with seven RBI.
- Among all MLB hitters, Ohtani is 111th in batting average, 148th in on-base percentage, and 71st in slugging.
- Ohtani has collected a hit in three games in a row. During his last five outings he is hitting .273 with three home runs, two walks and seven RBI.
- Brandon Marsh has capitalized on opportunities as he leads his team with eight RBI.
- Mike Trout is hitting .269 with three doubles, a home run and five walks.
- Jack Mayfield is hitting .360 with a double, a triple, a home run and two walks.
- Mayfield takes a three-game streak with at least one hit into this one. In his last five games he is hitting .316 with a triple, two walks and two RBI.
| Name | GP | BA | OBP | SLG | HR | RBI | H |
|---|---|---|---|---|---|---|---|
| Shohei Ohtani | 11 | .213 | .245 | .426 | 3 | 7 | 10 |
| Brandon Marsh | 9 | .250 | .355 | .458 | 1 | 8 | 6 |
| Mike Trout | 8 | .269 | .406 | .500 | 1 | 2 | 7 |
| Jack Mayfield | 7 | .360 | .429 | .600 | 1 | 3 | 9 |
| Jared Walsh | 9 | .323 | .344 | .516 | 2 | 6 | 10 |
Astros Leaders & Batting Stats
- Alex Bregman has driven in a team-best eight runs batted in.
- Among all batters in the big leagues, Bregman is 26th in homers and 18th in RBI.
- Jeremy Pena is batting .333 to lead the lineup.
- Pena is currently 26th in home runs and 97th in RBI in the big leagues.
- Yordan Alvarez leads the Astros with three long balls.
- Michael Brantley is batting .293 with two doubles, a home run and four walks.
| Name | GP | BA | OBP | SLG | HR | RBI | H |
|---|---|---|---|---|---|---|---|
| Alex Bregman | 11 | .263 | .356 | .474 | 2 | 8 | 10 |
| Jeremy Pena | 10 | .333 | .375 | .639 | 2 | 4 | 12 |
| Yordan Alvarez | 6 | .227 | .346 | .682 | 3 | 6 | 5 |
| Michael Brantley | 10 | .293 | .356 | .415 | 1 | 5 | 12 |
| Kyle Tucker | 11 | .103 | .222 | .256 | 2 | 4 | 4 |
Betting Tips for Angels vs. Astros
After digging through all of the key statistics and trends for this matchup, our best bet is the Astros on the moneyline at +115. Our computer prediction sees the scoring going over the total of 8.5 runs.

