Miami Marlins vs. St. Louis Cardinals Prediction, Betting Tips & Picks 4/20/2022

The St. Louis Cardinals (6-3) will look to Nolan Arenado, with homers in two straight games, to pull off an upset win over the Miami Marlins (4-5) Wednesday at loanDepot park. The Marlins are -132 moneyline favorites for the game, which starts at 6:40 PM ET. Sandy Alcantara will get the ball for Miami while St. Louis counter with Miles Mikolas.

Miami Marlins vs. St. Louis Cardinals: Predictions, Betting Odds, Spread, Line

Computer Predictions for Marlins vs. Cardinals

Our computer pick: St. Louis Cardinals (+113) and Over (7.5)

Marlins vs. Cardinals Game Info

• Miami Marlins probable starting pitcher: Sandy Alcantara
• St. Louis Cardinals probable starting pitcher: Miles Mikolas
• Game Day: Wednesday, April 20, 2022
• Game Time: 6:40 PM ET
• Location: Miami, Florida
• Stadium: loanDepot park

Miami Marlins vs St. Louis Cardinals Pitching Matchup

Marlins Starter Sandy Alcantara

• Alcantara (1-0) makes the start for the Marlins, his third of the season.
• His most recent appearance came on Thursday against the Philadelphia Phillies, when the righty went 6 1/3 innings, surrendering two earned runs while giving up seven hits.
• In his two games this season, opposing hitters have a collective batting average of .250 against him. He has a 3.18 ERA and averages 7.1 strikeouts per nine innings.
• The opposing Cardinals offense has the third-ranked slugging percentage (.441) and is sixth in MLB play with 12 home runs. It has a collective .251 batting average, and is 19th in MLB with 75 total hits and ninth in MLB play scoring 48 runs.
• Among qualifying pitchers in MLB action this season, the 26-year-old’s 3.18 ERA ranks 25th, 1.412 WHIP ranks 41st, and 7.1 K/9 ranks 36th.

Cardinals Starter Miles Mikolas

• Mikolas heads to the mound for the Cardinals to make his third start of the season, seeking his second win.
• The right-hander’s last appearance was on Saturday, when he threw 6 2/3 innings, giving up one earned run while allowing three hits against the Milwaukee Brewers.
• He has an ERA of 2.61, a batting average against of .231 and 7.0 strikeouts per nine innings in two games this season.
• He has earned a quality start one time in two starts this season.
• In two starts this season, Mikolas has lasted five or more innings one time, with an average of 5.1 innings per appearance.
• The Marlins have scored 37 runs this season, which ranks 23rd in MLB. They are batting .238 for the campaign with seven home runs, 27th in the league.
• Among qualified pitchers in the majors this campaign, the 33-year-old ranks 21st in ERA (2.61), 30th in WHIP (1.161), and 37th in K/9 (7.0).

Marlins Betting Picks & Insights

• The Marlins have won both games they’ve played as favorites this season.
• Miami has not entered a game this season with shorter moneyline odds than -132.
• The Marlins have a 56.9% chance to win this game based on the implied probability of the moneyline.
• Miami’s games have gone over the total in three of their nine chances.
• The Marlins are 6-3-0 ATS in their nine games with a spread this season.

Cardinals Betting Picks & Insights

• The Cardinals have come away with two wins in the four contests they have been listed as the underdogs in this season.
• This season, St. Louis has been victorious one time in three chances when named as an underdog of at least +113 or worse on the moneyline.
• The moneyline set for this matchup implies the Cardinals have a 46.9% chance of walking away with the win.
• St. Louis and its opponents have gone over the total this season in five of their nine opportunities.
• In nine games with a line this season, the Cardinals have a mark of 6-3-0 against the spread.

Marlins Leaders & Batting Stats

• Jesus Sanchez has launched a team-best two home runs.
• Among all MLB hitters, Sanchez is 16th in batting average, 40th in on-base percentage, and 10th in slugging.
• Jazz Chisholm has shown his power as he leads his team with two home runs and 10 runs batted in.
• Chisholm ranks 26th in homers and sixth in RBI in the major leagues.
• Joey Wendle has a team-best batting average of .385.
• Wendle is on a four-game hitting streak entering this contest. During his last five outings he is batting .375 with two doubles, a walk and four RBI.
• Bryan De La Cruz is batting .500 with a home run and three walks.

Cardinals Leaders & Batting Stats

• Arenado leads the squad with a batting average of .382, while pacing the Cardinals in home runs, with four and runs batted in with 12.
• Among all batters in the majors, Arenado ranks fourth in homers and fourth in RBI.
• Arenado takes a hitting streak of four games into this game. In his last five games he is batting .333 with two doubles, a home run, four walks and three RBI.
• Tommy Edman is hitting .355 with a double, a triple, three home runs and three walks.
• Edman is eighth overall in home runs and 30th in RBI this year.
• Tyler O’Neill has a double, a home run and five walks while batting .281.
• Albert Pujols is hitting .389 with a double, two home runs and two walks.

Betting Tips for Marlins vs. Cardinals

After analyzing all of the key trends and statistics for this matchup, our best bet is the Cardinals on the moneyline at +113. Our computer picks see the scoring going over the total of 7.5 runs.