Milwaukee Brewers vs. St. Louis Cardinals Prediction, Betting Tips & Picks 4/16/2022

Nolan Arenado leads the St. Louis Cardinals (4-2) into Saturday’s matchup with the Milwaukee Brewers (4-4) on a two-game homer streak. His Cardinals are underdogs for the contest, however, with sportsbooks naming the Brewers as -120 moneyline favorites. The game starts at 7:10 PM ET from American Family Field. Milwaukee’s Adrian Houser gets the start, and he’ll go against St. Louis’ Steven Matz.

Milwaukee Brewers vs. St. Louis Cardinals: Predictions, Betting Odds, Spread, Line

Computer Predictions for Brewers vs. Cardinals

Our computer pick: St. Louis Cardinals (+100) and Over (8.5)

Brewers vs. Cardinals Game Info

• Milwaukee Brewers probable starting pitcher: Adrian Houser
• St. Louis Cardinals probable starting pitcher: Steven Matz
• Game Day: Saturday, April 16, 2022
• Game Time: 7:10 PM ET
• Location: Milwaukee, Wisconsin
• Stadium: American Family Field

Milwaukee Brewers vs St. Louis Cardinals Pitching Matchup

Brewers Starter Adrian Houser

• Houser (0-1) pitches for the Brewers to make his second start of the season.
• The righty last appeared on Monday against the Baltimore Orioles, when he threw 3 2/3 innings, allowing two earned runs while giving up four hits.
• In one appearances this season, he has a 4.91 ERA and 7.4 strikeouts per nine innings, while opponents are batting .267 against him.
• The opposing Cardinals offense has a collective .271 batting average, and is 17th in the league with 54 total hits and sixth in MLB play with 36 runs scored. It has the best slugging percentage (.492) and ranks second in home runs (11) in all of MLB.

Cardinals Starter Steven Matz

• Matz will take to the mound for the Cardinals, his second start of the season.
• The left-hander last pitched on Sunday against the Pittsburgh Pirates, throwing 3 2/3 innings and giving up seven earned runs.
• He has an ERA of 21.00, a batting average against of .500 and 15 strikeouts per nine innings in one games this season.
• The Brewers rank 22nd in MLB with a .216 batting average this season. They have a team slugging percentage that ranks 23rd in the league (.336) and four home runs.

Brewers Betting Picks & Insights

• The Brewers have won four of the eight games they’ve played as favorites this season.
• This season, Milwaukee has won four of its eight games when favored by at least -120 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Brewers have a 54.5% chance to win.
• Games involving Milwaukee have gone over the total set by oddsmakers in three of eight chances this season.
• In eight games with a spread this season, the Brewers are 2-6-0 ATS.

Cardinals Betting Picks & Insights

• The Cardinals have split the two games they have played as underdogs this season.
• St. Louis has been listed as an underdog of +100 or more on two occasions this season and split those games.
• The moneyline set for this matchup implies the Cardinals have a 50% chance of walking away with the win.
• St. Louis’ games have gone over the total in four of their six opportunities.
• The Cardinals are 3-3-0 against the spread in their six games that had a posted line this season.

Brewers Leaders & Batting Stats

• Hunter Renfroe accumulated 31 home runs and had 96 runs batted in last season.
• Andrew McCutchen hit .222 with 24 doubles, a triple, 27 home runs and 81 walks.
• Willy Adames racked up 130 hits with a batting average of .262 last season.
• Kolten Wong had 32 doubles, two triples, 14 home runs and 31 walks while hitting .272.

Cardinals Leaders & Batting Stats

• Arenado leads the Cardinals with four home runs and 12 runs batted in, while posting a team-best batting average of .435.
• Arenado ranks second in homers and second in RBI among all hitters in the big leagues.
• Arenado carries a four-game hitting streak into this matchup. In his last five games he is hitting .474 with three doubles, three home runs, two walks and 10 RBI.
• Tommy Edman is hitting .368 with a double, three home runs and three walks.
• Among all major league hitters, Edman ranks third in homers and 61st in RBI.
• Tyler O’Neill has a double, a home run and two walks while batting .273.
• Paul Goldschmidt is hitting .190 with a double and five walks.

Betting Tips for Brewers vs. Cardinals

Our best bet is the Cardinals on the moneyline at +100 after looking at all of the key statistics and trends for this matchup. Our computer predicts the scoring will over the total of 8.5 runs.