Oakland Athletics vs. Baltimore Orioles Prediction, Betting Tips & Picks 4/20/2022

The Oakland Athletics will look to pick up their seventh win of the season when they take on the Baltimore Orioles (3-8) Wednesday. The game begins at 6:07 PM ET on MLB Network, with the Athletics listed as -127 favorites on the moneyline. Daulton Jefferies will get the ball for Oakland while Baltimore counter with Jordan Lyles.

Oakland Athletics vs. Baltimore Orioles: Predictions, Betting Odds, Spread, Line

Computer Predictions for Athletics vs. Orioles

Our computer pick: Baltimore Orioles (+106) and Over (8)

Athletics vs. Orioles Game Info

• Oakland Athletics probable starting pitcher: Daulton Jefferies
• Baltimore Orioles probable starting pitcher: Jordan Lyles
• Game Day: Wednesday, April 20, 2022
• Game Time: 6:07 PM ET
• TV Channel: MLB Network
• Location: Oakland, California
• Stadium: Oakland Coliseum

Oakland Athletics vs Baltimore Orioles Pitching Matchup

Athletics Starter Daulton Jefferies

• The Athletics will look to Jefferies (1-1) in his third start of the season.
• In his most recent appearance on Friday, the righty tossed 4 1/3 innings against the Toronto Blue Jays, allowing two earned runs while surrendering seven hits.
• Over his two appearances this season, opposing hitters have compiled a batting average of .257 against him. He has a 1.93 ERA and averages 3.9 strikeouts per nine innings.
• He will take the mound against an Orioles squad that is batting .209 as a unit (24th in MLB). It is also slugging a collective .289 (28th in MLB) with four total home runs (30th in MLB).

Orioles Starter Jordan Lyles

• Lyles heads to the mound for the Orioles to make his third start of the season, seeking his first win.
• The right-hander last pitched on Friday, when he threw 5 1/3 innings against the New York Yankees, giving up one earned run.
• He has an ERA of 5.23, a batting average against of .325 and 5.2 strikeouts per nine innings in two games this season.
• In two starts this season, Lyles has lasted five or more innings two times, with an average of 5.1 innings per appearance.
• The Athletics rank 25th in MLB with a .208 batting average this season. They have a team slugging percentage that ranks 26th in the league (.314) and eight home runs.

Athletics Betting Picks & Insights

• The Athletics have won both games they’ve played as favorites this season.
• Oakland has played as a favorite of -127 or more twice this season and won both games.
• The implied probability of a win from the Athletics, based on the moneyline, is 55.9%.
• Oakland and its opponents have gone over the total this season in four of their 11 opportunities.
• In 11 games with a spread this season, the Athletics are 7-4-0 ATS.

Orioles Betting Picks & Insights

• The Orioles have been chosen as underdogs in 11 games this year and have walked away with the win three times (27.3%) in those games.
• This season, Baltimore has come away with a win three times in 10 chances when named as an underdog of at least +106 or worse on the moneyline.
• The Orioles have an implied victory probability of 48.5% according to the moneyline set by oddsmakers for this matchup.
• In 11 contests with a total set by sportsbooks, Baltimore and its opponents have failed to hit the over in every contest.
• The Orioles have posted a record of 6-5-0 against the spread this season.

Athletics Leaders & Batting Stats

• Sean Murphy’s two homers in 2022 are the most on the Athletics. He’s also knocked in seven runs while hitting .233.
• Murphy’s home runs put him 26th in MLB, and he is 30th in RBI.
• Elvis Andrus is batting .206 with three doubles and seven walks.
• Andrus ranks 184th in homers and 330th in RBI among all hitters in the majors.
• Tony Kemp paces the Athletics with a .242 batting average.
• Kemp is on a two-game hitting streak entering this contest. In his last five games he is hitting .231 with four walks.
• Seth Brown has collected eight runs batted in to pace his team.

Orioles Leaders & Batting Stats

• Anthony Santander leads the Orioles with a .273 batting average.
• In all of MLB, Santander is 76th in home runs and 261st in RBI.
• Cedric Mullins has been a reliable source of runs this year, leading the lineup with two home runs and eight RBI.
• Mullins is 26th in homers and 18th in RBI among all hitters in the big leagues.
• Austin Hays has three doubles and six walks while hitting .220.
• Jorge Mateo has two doubles and four walks while batting .270.

Betting Tips for Athletics vs. Orioles

Our best bet is the Orioles on the moneyline at +106 after looking at all of the key stats and trends for this matchup. Our computer projects the total score will over the total of 8 runs.