Panthers vs. Browns Prediction, Betting Tips & Picks – Week 1

by | Sep 1, 2022

The Carolina Panthers (0-0) host the Cleveland Browns (0-0) at Bank of America Stadium on Sunday, September 11, 2022. Find more below on the Panthers vs. Browns betting line, injury report, head-to-head stats, best bets and more.

The Panthers (-2.5) are slight favorites against the Browns. The total is set at 41.5 points.

Panthers vs. Browns Spread and Betting Line

Panthers vs Browns Betting Information
Favorite Spread Favorite spread odds Underdog spread odds Total Over total odds Under total odds
Panthers -2.5 -109 -111 41.5 -110 -110

Panthers vs. Browns Game Info

  • Game Day: Sunday, September 11, 2022
  • Game Time: 1:00 PM ET
  • TV Channel: CBS
  • Location: Charlotte, North Carolina
  • Stadium: Bank of America Stadium

Panthers vs. Browns Prediction and Computer Picks

Prediction for Panthers vs Browns
Spread Pick Total Pick Predicted Score
Browns (+2.5) Over (41.5) Browns 23, Panthers 19

Panthers vs. Browns Betting Trends

  • The Panthers were 5-12-0 against the spread last year.
  • The Panthers won twice ATS (2-4) as a 2.5-point favorite or greater last year.
  • Last year, eight of the Panthers’ 17 games hit the over.
  • The average points scored by the Panthers last season, 17.9, was 3.9 fewer than the 21.8 the Browns gave up per game.
  • The Panthers were 3-2 overall when scoring over 21.8 points last season.
  • The Browns’ defense surrendered 311.5 yards per game last season, just 12.6 yards more than the 298.9 the Panthers’ offense averaged. The Panthers picked up 4.9 yards per play, while the Browns allowed 5.3.
  • In contests where the Panthers offense totaled more than the Browns’ average yard allowance last year (311.5), they were 5-3.
  • Carolina Panthers Leaders

  • Last season Baker Mayfield put up 3,010 yards (177.1 per game), a 60.5% completion percentage, 17 touchdowns, and 13 interceptions.
  • Chuba Hubbard rushed for 612 yards last season on 172 carries (36.0 yards per game) and scored five times.
  • In the previous season, D.J. Moore grabbed 93 passes (on 163 targets) for 1,157 yards (68.1 per game). He also found the end zone four times.
  • Brian Burns amassed 9.0 sacks, 13.0 TFL and 50 tackles last season.
  • Xavier Woods’ stat line last year included 107 tackles, 1.0 TFL, one sack, and three interceptions.
  • Carolina Panthers Season Stats

    Stat Average (Total) Rank
    Pass yards 190.5 (3239) 29
    Rush yards 108.4 (1842) 20
    Points scored 17.9 (304) 29
    Pass yards against 192.1 (3266) 4
    Rush yards against 113.8 (1935) 18
    Points allowed 23.8 (404) 21

    Browns vs. Panthers Betting Trends

  • The Browns had seven wins in 17 games against the spread last year.
  • The Browns had an ATS record of 3-3 as underdogs of 2.5 points or greater last year.
  • In 17 Browns games last season, seven of them hit the over.
  • The Panthers allowed 23.8 points per game last year, 3.3 more than the 20.5 the Browns scored.
  • The Browns were 4-2 overall when scoring over 23.8 points last year.
  • The Browns’ offense held a 34.7-yard advantage in yards gained per game versus yards conceded by the Panthers’ defense last season (340.6 to 305.9). The Browns averaged 5.8 yards per play, while the Panthers surrendered 5.3.
  • The Browns’ record last season when they accumulated more than the Panthers’ season average in total yards conceded (305.9): 7-4.
  • Cleveland Browns Leaders

  • Jacoby Brissett threw for an average of 75.5 yards passing per outing and tossed five touchdowns last season.
  • Nick Chubb tallied 1,259 rushing yards and eight touchdowns on the ground during last year’s campaign.
  • Amari Cooper averaged 50.9 yards on four receptions per game and racked up eight receiving touchdowns in 2021.
  • Last year Myles Garrett put pressure on opposing quarterbacks with 16.0 sacks, and added 17.0 TFL and 51 tackles.
  • Anthony Walker had a stellar defensive performance last season with 113 tackles, 2.0 TFL, and one sack.
  • Last year John Johnson intercepted three passes to go along with 59 tackles, 1.0 TFL, 0.5 sacks, and five passes defended.
  • Cleveland Browns Season Stats

    Stat Average (Total) Rank
    Pass yards 195.3 (3320) 27
    Rush yards 145.4 (2471) 4
    Points scored 20.5 (349) 20
    Pass yards against 202.3 (3439) 5
    Rush yards against 109.2 (1857) 12
    Points allowed 21.8 (371) 13

    Panthers and Browns Injury Report

    Player Pos. Injury Status
    Player Pos. Injury Status

    Panthers and Browns’ Recent Performance

    The Panthers fell short of the playoffs a year ago after going 5-12. They averaged 17.9 points per game (29th in the league) while their defense allowed 23.8 (21st). The Browns’ 2021 season ended without a playoff berth after an 8-9 regular season record. They averaged 20.5 points per game (20th in the NFL) and gave up 21.8 per contest (13th).

    Betting Tips for Panthers vs. Browns

    Our best bet against the spread is Browns (+2.5) after taking a look at all of the key stats and trends for this matchup. Our computer projects the scoring will finish over the total of 41.5 points, with a final score of Browns 23, Panthers 19.

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