San Francisco Giants vs. San Diego Padres MLB Betting Tips and Best Bets

The San Diego Padres (3-1) will put their three-game win streak to the test when they visit the San Francisco Giants (2-1) Monday at 9:45 PM ET. Bookmakers consider the Giants to be -142 favorites, while the Padres are +122 underdogs to keep their streak alive. San Francisco’s Alex Wood and San Diego’s Nick Martinez have been named the starters for this contest.

San Francisco Giants vs. San Diego Padres: Predictions, Betting Odds, Spread, Line

Computer Predictions for Giants vs. Padres

Our computer pick: San Diego Padres (+122) and Over (8.5)

Giants vs. Padres Game Info

• San Francisco Giants probable starting pitcher: Alex Wood
• San Diego Padres probable starting pitcher: Nick Martínez
• Game Day: Monday, April 11, 2022
• Game Time: 9:45 PM ET
• Location: San Francisco, California
• Stadium: Oracle Park

San Francisco Giants vs San Diego Padres Pitching Matchup

Giants Starter Alex Wood

• Wood will start for the Giants, his first of the season.
• The 31-year-old southpaw started and threw 4 2/3 scoreless innings when he last appeared on Tuesday, Oct. 12 against the Los Angeles Dodgers.
• Over his 26 appearances last season he put together a 10-4 record and had a 3.83 ERA and a 1.183 WHIP.

Padres Starter Nick Martínez

• The Padres will send Martinez to the mound for his first start this season.
• The 31-year-old right-hander will make his season debut.

Giants Betting Picks & Insights

• Last season, the Giants were favored 98 times and won 70, or 71.4%, of those games.
• San Francisco had a record of 51-16 in games where oddsmakers favored them by at least -142 on the moneyline.
• The moneyline for this contest implies a 58.7% chance of a victory for the Giants.
• Last season, San Francisco and its opponents hit the over in 74 of their 164 games with a total.
• The Giants were 74-46-0 against the spread last season.

Padres Betting Picks & Insights

• The Padres were victorious in 10, or 23.3%, of the 43 contests they were chosen as underdogs in last season.
• San Diego had a win-loss record of 5-14 when favored by +122 or worse by sportsbooks last year.
• Sportsbooks have implied with the moneyline set for this matchup that the Padres have a 45% chance of pulling out a win.
• San Diego’s games went over the total in 82 of its 159 opportunities.
• The Padres went 58-60-0 against the spread in their 118 games with a line set by sportsbooks last season.

Giants Leaders & Batting Stats

• Brandon Crawford had 90 runs batted in while accumulating a batting average of .298 last season.
• Mike Yastrzemski had 28 doubles, three triples, 25 home runs and 51 walks while hitting .224.
• Wilmer Flores hit .262 last season with 16 doubles, a triple, 18 home runs and 41 walks.
• Brandon Belt racked up 29 home runs a season ago while slugging .597.

Padres Leaders & Batting Stats

• Manny Machado plated 106 runs last season, while batting .278.
• Jake Cronenworth hit .266 with 33 doubles, seven triples, 21 home runs and 55 walks.
• Eric Hosmer hit .269 a season ago with 28 doubles, 12 home runs and 48 walks.
• Trent Grisham hit .242 with 28 doubles, three triples, 15 home runs and 54 walks.

Betting Tips for Giants vs. Padres

Our best bet is the Padres on the moneyline at +122 after analyzing all of the key stats and trends for this matchup. Our computer projects the total score will over the total of 8.5 runs.