Twins vs. Guardians Prediction, Betting Tips & Picks 6/21/2022

A pair of division rivals take the field Tuesday when the first-place Minnesota Twins (38-30) host the second-place Cleveland Guardians (34-28). Sportsbooks favor the Twins (-171) for the contest, which starts at 7:40 PM ET. Joe Ryan gets the starting nod for Minnesota while Aaron Civale is Cleveland’s starter for the contest.

Twins vs. Guardians Spread and Betting Line

Computer Predictions for Twins vs. Guardians

Our computer pick: Cleveland Guardians (+147) and Over (9.5)

Twins vs. Guardians Game Info

• Minnesota Twins probable starting pitcher: Joe Ryan
• Cleveland Guardians probable starting pitcher: Aaron Civale
• Game Day: Tuesday, June 21, 2022
• Game Time: 7:40 PM ET
• Location: Minneapolis, Minnesota
• Stadium: Target Field

Minnesota Twins vs Cleveland Guardians Pitching Matchup

Twins Starter Joe Ryan

• Ryan gets the start for the Twins, his 10th of the season. He is 5-3 with a 2.81 ERA and 45 strikeouts in 48 innings pitched.
• The right-hander’s most recent appearance came on Wednesday against the Seattle Mariners, when he went 4 2/3 innings, surrendering four earned runs while allowing five hits.
• In nine games this season, the 26-year-old has a 2.81 ERA and 8.4 strikeouts per nine innings, while giving up a batting average of .194 to his opponents.
• Ryan heads into the outing with four quality starts under his belt this season.
• Ryan is looking to record his sixth start of five or more innings this season in this game.
• He will match up with a Guardians offense that ranks 21st in MLB with 524 total hits (on a .249 batting average). The team also slugs a collective .386 (17th in MLB) with 48 total home runs (28th in MLB).
• Ryan has pitched six innings, giving up one earned run on four hits while striking out five against the Guardians this season.

Guardians Starter Aaron Civale

• Civale has been named the starter for the Guardians and will make his first start this season.
• The 27-year-old right-hander will make his season debut.
• The Twins have scored 300 runs this season, which ranks 13th in MLB. They are batting .251 for the campaign with 77 home runs, 11th in the league.

Twins Betting Picks & Insights

• The Twins have won 26, or 65%, of the 40 games they’ve played as favorites this season.
• Minnesota is 8-2 this season when entering a game favored by -171 or more on the moneyline.
• The Twins have a 63.1% chance to win this game based on the implied probability of the moneyline.
• Games involving Minnesota have gone over the total set by oddsmakers in 31 of 68 chances this season.
• The Twins are 32-36-0 against the spread this season.

Guardians Betting Picks & Insights

• The Guardians have been chosen as underdogs in 35 games this year and have walked away with the win 16 times (45.7%) in those games.
• Cleveland has a mark of 5-8 in contests where bookmakers favor them by +147 or worse on the moneyline.
• The Guardians have an implied victory probability of 40.5% according to the moneyline set for this matchup.
• Contests with Cleveland have gone over the total set by bookmakers in 32 of 67 chances this season.
• In 67 games with a line this season, the Guardians have a mark of 36-31-0 against the spread.

Twins Leaders & Batting Stats

• Luis Arraez is the Twins best hitter so far this season, hitting at a team-leading .361 rate along with three homers and 21 RBI.
• Among all batters in the majors, Arraez’s home run total ranks him 228th, and his RBI tally ranks him 162nd.
• Arraez has collected a hit in four straight games. During his last five outings he is batting .353 with two doubles, two walks and two RBI.
• Byron Buxton’s 19 home runs and 33 runs batted in both lead his team.
• Buxton is third in homers in baseball, and 52nd in RBI.
• Buxton heads into this game looking for his third game in a row with a hit. In his last five games he is batting .250 with a double, two home runs, three walks and three RBI.
• Max Kepler is hitting .244 with 10 doubles, a triple, six home runs and 27 walks.
• Gio Urshela is hitting .257 with 10 doubles, five home runs and 19 walks.

Guardians Leaders & Batting Stats

• Jose Ramirez paces the Guardians with 16 home runs and 62 runs batted in, while recording a team-high batting average of .310.
• Among all hitters in the majors, Ramirez is 13th in home runs and second in RBI.
• Ramirez has collected a hit in nine straight games. In his last 10 games he is hitting .390 with eight doubles, two home runs, two walks and nine RBI.
• Owen Miller is batting .262 with 18 doubles, four home runs and 17 walks.
• Miller is 184th among all hitters in the majors in homers, and 72nd in RBI.
• Josh Naylor is batting .277 with 12 doubles, seven home runs and 14 walks.
• Amed Rosario is hitting .265 with 10 doubles, four triples, a home run and 11 walks.

Betting Tips for Twins vs. Guardians

We have the Guardians on the moneyline at +147 on the moneyline as our best bet in this game after digging through all of the key statistics and trends for this matchup. Our computer prediction sees the scoring going over the total of 9.5 runs.