Twins vs. Guardians Prediction, Betting Tips & Picks 6/22/2022

The Cleveland Guardians (35-28) and Steven Kwan, coming off a four-hit game, are underdogs (+128) on the moneyline and will look to upset the Minnesota Twins (38-31) on Wednesday at 7:40 PM ET. Minnesota’s Sonny Gray and Cleveland’s Triston McKenzie have been named the starters for this contest.

Twins vs. Guardians Spread and Betting Line

Computer Predictions for Twins vs. Guardians

Our computer pick: Cleveland Guardians (+128) and Over (8.5)

Twins vs. Guardians Game Info

• Minnesota Twins probable starting pitcher: Sonny Gray
• Cleveland Guardians probable starting pitcher: Triston McKenzie
• Game Day: Wednesday, June 22, 2022
• Game Time: 7:40 PM ET
• Location: Minneapolis, Minnesota
• Stadium: Target Field

Minnesota Twins vs Cleveland Guardians Pitching Matchup

Twins Starter Sonny Gray

• Gray (3-1 with a 2.09 ERA and 42 strikeouts in 38 2/3 innings pitched) makes the start for the Twins, his ninth of the season.
• His last appearance came on Wednesday against the Seattle Mariners, when the right-hander tossed 5 2/3 scoreless innings while allowing three hits.
• In eight games this season, the 32-year-old has put up an ERA of 2.09, with 9.8 strikeouts per nine innings. Opponents are hitting .184 against him.
• Gray enters the outing with three quality starts under his belt this year.
• Gray will look to last five or more innings for his fifth straight start. He’s averaging 4.3 frames per outing.
• The opposing Guardians offense has a collective .249 batting average, and is 20th in the league with 536 total hits and 18th in MLB play with 289 runs scored. It has the 18th-ranked slugging percentage (.387) and ranks 28th in home runs (50) in all of MLB.
• In 4 1/3 innings over one appearance against the Guardians this season, Gray has a 4.15 ERA and a 1.846 WHIP while his opponents are batting .235.

Guardians Starter Triston McKenzie

• The Guardians will send McKenzie (4-5) to the mound for his 12th start this season.
• The right-hander gave up one earned run in 6 2/3 innings pitched on Thursday in his last outing, a matchup with the Colorado Rockies.
• The 24-year-old has an ERA of 2.96 and 7.8 strikeouts per nine innings with an opponent batting average of .185 in 12 games this season.
• He’s going for his third quality start in a row.
• McKenzie has pitched five or more innings in nine straight games and will look to extend that streak.
• The Twins rank eighth in MLB with a .251 batting average this season. They have a team slugging percentage that ranks eighth in the league (.408) and 78 home runs.
• This season, the right-hander has pitched against the Twins in one game, and they have gone 3-for-24 with two home runs and three RBI over seven innings.
• Among qualified pitchers this season, the 24-year-old’s 2.96 ERA ranks 25th, .929 WHIP ranks seventh, and 7.8 K/9 ranks 35th.

Twins Betting Picks & Insights

• The Twins have entered the game as favorites 41 times this season and won 26, or 63.4%, of those games.
• Minnesota has a record of 13-5, a 72.2% win rate, when favored by -150 or more by sportsbooks this season.
• The Twins have a 60% chance to win this game based on the implied probability of the moneyline.
• So far this season, Minnesota and its opponents have hit the over in 32 of their 69 games with a total.
• In 69 games with a spread this season, the Twins are 32-37-0 ATS.

Guardians Betting Picks & Insights

• The Guardians have been victorious in 17, or 47.2%, of the 36 contests they have been chosen as underdogs in this season.
• This season, Cleveland has come away with a win eight times in 19 chances when named as an underdog of at least +128 or worse on the moneyline.
• The Guardians have an implied victory probability of 43.9% according to the moneyline set for this matchup.
• Contests with Cleveland have gone over the total set by bookmakers in 33 of 68 chances this season.
• In 68 games with a line this season, the Guardians have a mark of 37-31-0 against the spread.

Twins Leaders & Batting Stats

• The Twins best hitter so far this season is Luis Arraez, who’s hitting at a team-leading .362 clip along with four homers and 24 RBI.
• In all of the majors, Arraez is 189th in home runs and 140th in RBI.
• Arraez brings a hitting streak of five games into this game. During his last five outings he is batting .444 with three doubles, a home run, two walks and five RBI.
• Byron Buxton’s 19 home runs and 33 runs batted in both lead his team.
• Buxton is fourth in home runs and 60th in RBI among all major league hitters this year.
• Max Kepler is hitting .243 with 10 doubles, a triple, six home runs and 27 walks.
• Gio Urshela is batting .251 with 10 doubles, five home runs and 19 walks.

Guardians Leaders & Batting Stats

• Jose Ramirez leads the Guardians with 16 home runs and 62 runs batted in, while posting a team-high batting average of .307.
• In all of MLB, Ramirez is 13th in home runs and second in RBI.
• Ramirez takes a hitting streak of 10 games into this game. In his last 10 games he is hitting .405 with nine doubles, two home runs, two walks and nine RBI.
• Josh Naylor has 12 doubles, eight home runs and 15 walks while batting .283.
• Naylor ranks 76th in home runs and 33rd in RBI among all batters in MLB.
• Owen Miller is hitting .262 with 18 doubles, four home runs and 17 walks.
• Kwan is batting .281 with seven doubles, two triples, a home run and 22 walks.

Betting Tips for Twins vs. Guardians

After taking a look at all of the key trends and statistics for this matchup, our best bet is the Guardians on the moneyline at +128. Our computer picks see the scoring going over the total of 8.5 runs.