Yankees vs. White Sox Prediction, Betting Tips & Picks 5/21/2022

Coming off of a 3-1 series win over the Orioles, the New York Yankees (28-10) are -182 favorites to pick up the win in Game 1 of a three-game series against the Chicago White Sox (19-19). The series begins at Yankee Stadium, starting on Saturday at 1:05 PM ET. New York’s Nestor Cortes and Chicago’s Dallas Keuchel have been named the starters for this contest.

Yankees vs. White Sox Spread and Betting Line

Computer Predictions for Yankees vs. White Sox

Our computer pick: Chicago White Sox (+160) and Over (9)

Yankees vs. White Sox Game Info

• New York Yankees probable starting pitcher: Nestor Cortes
• Chicago White Sox probable starting pitcher: Dallas Keuchel
• Game Day: Saturday, May 21, 2022
• Game Time: 1:05 PM ET
• Location: The Bronx, New York
• Stadium: Yankee Stadium

New York Yankees vs Chicago White Sox Pitching Matchup

Yankees Starter Nestor Cortes

• Nestor Cortes Jr. (2-1 with a 1.35 ERA and 49 strikeouts in 40 innings pitched) gets the start for the Yankees, his eighth of the season.
• The lefty’s most recent time out was on Sunday against the Chicago White Sox, when he tossed eight innings, surrendering one earned run while giving up three hits.
• In seven games this season, the 27-year-old has amassed a 1.35 ERA and 11.0 strikeouts per nine innings, while allowing a batting average of .164 to opposing hitters.
• Cortes is looking to claim his third straight quality start in this game.
• Cortes will aim to go five or more innings for his third straight appearance. He’s averaging 5.2 frames per outing.
• He will face a White Sox offense that ranks 25th in the league with 135 runs while batting .231 as a unit. It has a collective .353 slugging percentage (24th in MLB action) and has hit a total of 33 home runs (18th in MLB).
• In eight innings over one appearance against the White Sox this season, Cortes has a 1.13 ERA and a 0.375 WHIP while his opponents are batting .111.
• Among qualifying pitchers in MLB play this season, the 27-year-old ranks first in ERA (1.35), third in WHIP (.850), and fourth in K/9 (11.0).

White Sox Starter Dallas Keuchel

• Keuchel (2-3) will take the mound for the White Sox, his seventh start of the season.
• The left-hander last pitched on Saturday, when he allowed four hits in five scoreless innings against the New York Yankees.
• The 34-year-old has pitched to a 5.54 ERA this season with 5.5 strikeouts per nine innings compared to 5.2 walks per nine across six games.
• In six starts this season, he’s earned one quality start.
• Keuchel has pitched five or more innings in three straight games and will look to extend that streak.
• The Yankees are batting .244 this season, 10th in MLB. They have a team slugging percentage of .422 (second in the league) with 55 home runs.
• The Yankees have gone 4-for-18 with a double in five innings this season against the left-hander.

Yankees Betting Picks & Insights

• This season, the Yankees have won 25 out of the 35 games, or 71.4%, in which they’ve been favored.
• This season, New York has won 16 of its 20 games, or 80%, when favored by at least -182 on the moneyline.
• The moneyline for this contest implies a 64.5% chance of a victory for the Yankees.
• New York and its opponents have gone over the total this season in 16 of their 37 opportunities.
• In 37 games with a spread this season, the Yankees are 19-18-0 ATS.

White Sox Betting Picks & Insights

• The White Sox have been underdogs in 11 games this season and have come away with the win three times (27.3%) in those contests.
• Chicago has played as an underdog of +160 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies the White Sox have a 38.5% chance of walking away with the win.
• Chicago and its opponents have gone over the total this season in 15 of their 42 opportunities.
• The White Sox are 19-23-0 against the spread in their 42 games with a line set by sportsbooks this season.

Yankees Leaders & Batting Stats

• Aaron Judge has accumulated a team-best batting average of .307, and paces the Yankees in home runs (14).
• Among all MLB hitters, Judge is 15th in batting average, 17th in on-base percentage, and third in slugging.
• Anthony Rizzo is batting .234 with seven doubles, a triple, 10 home runs and 16 walks.
• Rizzo is sixth in homers and 17th in RBI on the season.
• Rizzo has four straight games with at least one hit. In his last five games he is hitting .238 with two doubles, a home run, a walk and an RBI.
• Giancarlo Stanton has racked up a team-best 35 runs batted in.
• Stanton will look to build on his three-game hitting in this game. During his last five outings he is hitting .368 with two doubles, a home run, four walks and five RBI.
• DJ LeMahieu is hitting .275 with nine doubles, two home runs and 13 walks.
• LeMahieu takes a two-game streak with at least one hit into this one. During his last five outings he is batting .190 with two walks and three RBI.

White Sox Leaders & Batting Stats

• Tim Anderson leads the team in batting average with a high-water mark of .346.
• Among all hitters in the big leagues, Anderson’s home run total ranks 74th and his RBI tally is 101st.
• Anderson carries a two-game hitting streak into this matchup. In his last five games he is batting .381 with two walks and three RBI.
• Luis Robert been a consistent power bat this season, as he paces his team with six home runs and 17 RBI.
• Among all major league hitters, Robert is 41st in home runs and 75th in RBI.
• Jose Abreu is batting .207 with seven doubles, three home runs and 17 walks.
• Andrew Vaughn is batting .267 with three doubles, four home runs and five walks.

Betting Tips for Yankees vs. White Sox

Our best bet is the White Sox on the moneyline at +160 after analyzing all of the key stats and trends for this matchup. Our computer projects the total score will over the total of 9 runs.